Summary
Effects of atrial natriuretic factor (ANF) on monkey, rabbit and dog internal carotid arteries were investigated. ANF caused a concentration-dependent relaxation in arterial strips submaximally precontracted with noradrenaline, 5-hydroxytryptamine, or high-potassium solution (10–30 mM). The response was greatest in the monkey arteries and least in the dog arteries. These results suggest that there is a marked species difference in the ANF-induced relaxation of the internal carotid arteries.
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Kawai, Y., Ohhashi, T. Responses of monkey, rabbit and dog internal carotid arteries to atrial natriuretic factor. Experientia 43, 568–570 (1987). https://doi.org/10.1007/BF02143587
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DOI: https://doi.org/10.1007/BF02143587