Summary
DNA clones have been isolated that span the complete mitochondrial (mt) genome of the dolphin,Cephalorhynchus commersonii. Hybridization experiments with purified primate mtDNA probes have established that there is close resemblance in the general organization of the dolphin mt genome and the terrestrial mammalian mt genomes. Sequences covering 2381 bp of the dolphin mt genome from the major noncoding region, three tRNA genes, and parts of the genes encoding cytochrome b, NADH dehydrogenase subunit 3 (ND3), and 16S rRNA have been compared with corresponding regions from other mammalian genomes. There is a general tendency throughout the sequenced regions for greater similarity between dolphin and bovine mt genomes than between dolphin and rodent or human mt genomes.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Anderson S, Bankier AT, Barrell BG, de Bruijn MHL, Coulson AR, Drouin IC, Eperon DP, Nielich DP, Roe BA, Sanger F, Schreier PH, Smith AJH, Staden R, Young IG (1981) Sequence and organization of the human mitochondrial genome. Nature 290:457–465
Anderson S, de Bruijn MHL, Coulson AR, Eperon IC, Sanger F, Young IG (1982) Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome. J Mol Biol 156:683–717
Barnes LG, Domning, DP, Ray CE (1985) Status of studies on fossil marine mammals. Mar Mamm Sci 1:15–53
Bibb MJ, Van Etten RA, Wright CT, Walberg MW, Clayton DA (1981) Sequence and gene organization of mouse mitochondrial DNA. Cell 26:167–180
Brown GG, Gadaleta G, Pepe G, Saccone C, Sbisà E (1986) Structural conservation and variation in the D-loop containing region of vertebrate mitochondrial DNA. J Mol Biol 192: 503–511
Brown WM, George M, Wilson AC (1979) Rapid evolution of animal mitochondrial DNA. Proc Natl Acad Sci USA 76: 1967–1971
Brown WM, Prager EM, Wang A, Wilson AC (1982) Mitochondrial DNA sequences of primates: tempo and mode of evolution. J Mol Evol 18:225–239
Chang DD, Clayton DA (1984) Precise identification of individual promoters for transcription of each strand of human mitochondrial DNA. Cell 36:635–643
Chomyn A, Mariottini P, Cleeter MWJ, Ragan CI, Matsuno-Yagi A, Hatefi Y, Doolittle RF, Attardi G (1985) Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase. Nature 314:592–597
Drouin J (1980) Cloning of human mitochondrial DNA inEscherichia coli. J Mol Biol 140:15–34
Ferris SD, Wilson AC, Brown WM (1981) Evolutionary tree for apes and humans based on cleavage maps of mitochondrial DNA. Proc Natl Acad Sci USA 78:2432–2436
Ferris SD, Sage RD, Huang C-M, Nielsen JT, Ritte U, Wilson AC (1983) Flow of mitochondrial DNA across a species boundary. Proc Natl Acad Sci USA 80:2290–2294
Gingerich PD, Wells NA, Russell DE, Shah SMI (1983) Origin of whales in epicontinental remnant seas: new evidence from the early eocene of Pakistan. Science 220:403–406
Higuchi R, Bowman B, Freiberger M, Ryder OA, Wilson AC (1984) DNA sequences from the quagga, an extinct member of the horse family. Nature 312:282–284
Lansman RA, Avise JC, Aquadro CF, Shapira JF, Daniel SW (1983) Extensive genetic variation in mitochondrial DNA's among geographic populations of the deer mouse,Peromyscus maniculatus. Evolution 37:1–16
Lukesová-Southern SO (1982) Function of the specific dynamics of phosphorus in the nucleotide structure: selective self-activation of C-G units. Conference on the Structural Dynamics of DNA. April 1982, Veldhoven, The Netherlands
Maxam AM, Gilbert W (1980) Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol 65: 499–560
Mignotte B, Dunon-Bluteau D, Reiss C, Mounolou J-C (1987) Sequence deduced physical properties in the D-loop region common to five vertebrate mitochondrial DNAs. J Theor Biol 124:57–69
Nei M, Li W-H (1979) Mathematical model for studying genetic variation in terms of restriction endonucleases. Proc Natl Acad Sci USA 76:5269–5273
Ojala D, Merkel C, Gelfand R, Attardi G (1980) The transfer RNA genes punctuate the reading of genetic information in human mitochondrial DNA. Cell 22:393–404
Olivo PD, Van de Walle MJ, Laipis PJ, Hauswirth WW (1983) Nucleotide sequence evidence for rapid genotypic shifts in the bovine mitochondrial DNA D-loop. Nature 306:400–402
Sekiya T, Kobayashi M, Seki T, Koike K (1980) Nucleotide sequence of a cloned fragment of rat mitochondrial DNA containing the replication origin. Gene 11:53–62
Shields GF, Wilson AC (1987) Calibration of mitochondrial DNA evolution in geese. J Mol Evol 24:212–217
Spolsky C, Uzzell T (1984) Natural interspecies transfer of mitochondrial DNA in amphibians. Proc Natl Acad Sci USA 81:5802–5805
Upholt WB, Dawid IB (1977) Mapping of mitochondrial DNA of individual sheep and goats: rapid evolution in the D-loop region. Cell 11:571–583
Watanabe T, Hayashi Y, Kimura J, Yasuda Y, Saitou N, Tomita T, Ogasawara N (1986) Pig mitochondrial DNA: polymorphism, restriction map orientation, and sequence data. Biochem Genet 24:385–396
Wright JW, Spolsky C, Brown WM (1983) The origin of the parthenogenetic lizardCnemidophorus laredoensis inferred from mitochondrial DNA analysis. Herpetologica 39:410–416
Zyskind JW, Cleary JM, Brusilow WSA, Harding NE, Smith DW (1983) Chromosomal replication origin from the marine bacteriumVibrio harveyi functions inEscherichia coli oriC consensus sequence. Proc Natl Acad Sci USA 80:1164–1168
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Southern, Š.O., Southern, P.J. & Dizon, A.E. Molecular characterization of a cloned dolphin mitochondrial genome. J Mol Evol 28, 32–42 (1988). https://doi.org/10.1007/BF02143495
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02143495