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Failure ofl-phenylalanine to prevent benzene-induced pancytopenia

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Zusammenfassung

In 2 Gruppen von Kaninchen wurden mittels s.c. Benzolinjektionen aplastische Anämien induziert. Bei der 2. Gruppe wurde gleichzeitigl-Phenylalanin verfüttert. Weder im Auftreten der peripheren Panzytopenie noch in der autoradiographisch erfassten Hemmung der DNS-Synthese waren signifikante Unterschiede vorhanden, undl-Phenylalanin erscheint auch in der Verhinderung der benzolinduzierten aplastischen Anämie wirkungslos.

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Literatur

  1. B. Speck, Th. Schnider, U. Gerber andS. Moeschlin, Schweiz. med. Wschr.96, 1274 (1966).

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Authors and Affiliations

  1. Medical Department and Radioisotope Laboratory of the Bürgerspital Solothurn, Switzerland

    B. Speck & S. Moeschlin

Authors
  1. B. Speck
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  2. S. Moeschlin
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Additional information

This study was supported by a grant of the Swiss National Foundation for Scientific Research (No. 4003).

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Speck, B., Moeschlin, S. Failure ofl-phenylalanine to prevent benzene-induced pancytopenia. Experientia 23, 481–482 (1967). https://doi.org/10.1007/BF02142190

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