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Frequency potentiation of synaptic response in medial bulbar tegmental neurons to microstimulation of the pontine inhibitory site

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Abstract

Synaptic response to single (2 Hz) and regular (30–50 Hz) stimuli applied to the pontine inhibitory site were recorded in decerebrate cats. A change to regular stimulation was usually accompanied by a rise in the firing index of synaptic discharges and raised amplitude of inhibitory and (to a lesser extent) excitatory postsynaptic potentials. Suppression of background spike activity was observed in some neurons. It was deduced that frequency potentiation makes a considerable contribution to the functional effect of stimulating the inhibitory site, i.e., terminating evoked locomotion.

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Authors
  1. V. A. Selionov
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  2. M. L. Shik
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Additional information

Institute for Information Transmission Studies, Academy of Sciences of the USSR, Moscow. Translated from Neirofiziologiya, Vol. 20, No. 2, pp. 172–180, March–April, 1988.

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Selionov, V.A., Shik, M.L. Frequency potentiation of synaptic response in medial bulbar tegmental neurons to microstimulation of the pontine inhibitory site. Neurophysiology 20, 126–132 (1988). https://doi.org/10.1007/BF02141327

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  • DOI: https://doi.org/10.1007/BF02141327

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