Skip to main content
SpringerLink
Log in

The influence of partial synchronization of cell growth on the inhibition of L1210 cell viability by mouse thymus DNA

  • Specialia
  • Anatomica. Histologica. Carcinologica
  • Published:
Experientia Aims and scope Submit manuscript

Résumé

Nous avons trouvé que le cycle de la vie de la cellule L1210 règle les effets inhibitoires du DNA du thymus de la souris sur la viabilité cellulaire. Les cellules obtenues à la phase G2 des cultures partiellement synchronisées étaient inhibitées presque 2 fois plus que les cellules obtenues des cultures asynchroniques. Le DNA n'avait guère d'effet toxique sur les cellules obtenues aux phases S et M. Les fluctuations dans la viabilité cellulaire n'étaient pas causées par des changements proportionnels dans l'absorption du DNA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. J. L. Glick andA. P. Salim, Nature213, 676 (1967).

    Article  CAS  Google Scholar 

  2. J. L. Glick andA. R. Goldberg, Science149, 997 (1965).

    Article  CAS  Google Scholar 

  3. J. L. Glick andA. R. Goldberg, Trans. N.Y. Acad. Sci.28, 741 (1966).

    Article  CAS  Google Scholar 

  4. J. L. Glick, Cancer Res.27, 175 (1967).

    CAS  Google Scholar 

  5. J. L. Glick, Cancer Res., in press.

  6. R. M. Halpern, B. C. Halpern, G. Ciliv andR. A. Smith, Biochem. Biophys. Res. Commun.24, 559 (1966).

    Article  CAS  Google Scholar 

  7. G. I. Floersheim, Experientia18, 328 (1962).

    Article  CAS  Google Scholar 

  8. A. G. Smith, Cancer Res.24, 603 (1964).

    CAS  Google Scholar 

  9. A. G. Smith andH. R. Cress, Lab. Invest.10, 898 (1961).

    CAS  Google Scholar 

  10. J. L. Glick, Expl Cell Res.45, 690 (1967).

    Article  CAS  Google Scholar 

  11. E. H. Szybalska andW. Szybalski, Proc. natn. Acad. Sci., U.S.A.48, 2026 (1962).

    Article  CAS  Google Scholar 

  12. J. L. Glick, Cancer Res., in press.

  13. E. W. Taylor, Expl Cell Res.40, 316 (1965).

    Article  CAS  Google Scholar 

  14. W. Schneider, inMethods in Enzymology (Ed.S. P. Colowick andN. O. Kaplan; Academic Press Inc., New York 1957), vol. 3, p. 680.

    Chapter  Google Scholar 

  15. J. E. Adams, W. E. Martin andC. E. Pomerat, Tex. Rep. Biol. Med.23, 191 (1965).

    Google Scholar 

  16. J. L. Glick andC. Sahler, Cancer Res., in press.

  17. C. Basilico andG. Marin, Virology28, 429 (1966).

    Article  CAS  Google Scholar 

  18. D. Axelrod, K. Habel andE. T. Bolton, Science146, 1466 (1964).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. New York State Department of Health, Roswell Park Memorial Institute, 14203, Buffalo, New York, USA

    H. A. Crystal & J. L. Glick

Authors
  1. H. A. Crystal
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. L. Glick
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This work was supported in part by grant No. GW-733 of the NSF and by grant No. CA-08763 of the USPHS.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Crystal, H.A., Glick, J.L. The influence of partial synchronization of cell growth on the inhibition of L1210 cell viability by mouse thymus DNA. Experientia 24, 380–381 (1968). https://doi.org/10.1007/BF02140833

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02140833

Keywords

Search

Navigation