Abstract
Lesions due to cytomegalovirus (CMV) are frequent in the immunocompromised patient. This is particularly the case in patients with AIDS, where the colon and rectum are the regions most often involved. The authors report six cases of anal ulcerations due to CMV in patients with AIDS. These lesions, confirmed histologically, were either isolated or associated with other localizations. Treatment is based on specific antiviral agents but resistance and recurrence can occur. The current report underlines the importance of histologic examination of anal lesions in HIV-infected subjects.
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References
Connolly GM, Shanson D, Hawkins DA, Harcourt Webster JN, Gazzard BG. Non-cryptosporidial diarrhoea in human immunodeficiency virus (HIV) infected patients. Gut 1989;30:195–200.
Rene E, Marche C, Chevalier T, et al. Cytomegalovirus colitis in patients with acquired immunodeficiency syndrome. Dig Dis Sci 1988;33:741–50.
Roussel JY, Chevalier T, Rene E. Infections digestives au cours du SIDA. Ann Gastroenterol Hepatol 1989;25:61–4.
Rabinowitz M, Bassan I, Robinson MJ. Sexually transmitted cytomegalovirus proctitis in a woman. Am J Gastroenterol 1988;83:885–7.
Drew WL, Mintz L, Miner RC, Sands M, Ketterer B. Prevalence of cytomegalovirus infection in homosexual men. J Infect Dis 1981;143:188–92.
Hyder JW, MacKeigan JM. Anorectal and colonic disease and the immunocompromised host. Dis Colon Rectum 1988;31:971–6.
Blackman E, Vimadalal S, Nash G. Significance of gastrointestinal cytomegalovirus infection in homosexual males. Am J Gastroenterol 1984;12:935–40.
Gazzard BG. HIV disease and the gastroenterologist. Gut 1988;29:1497–505.
Laughon BE, Druckman DA, Vernon A, et al. Prevalence of enteric pathogens in homosexual men with and without acquired immunodeficiency syndrome. Gastroenterology 1988;94:984–93.
Weber JN, Thom S, Barrison I, et al. Cytomegalovirus colitis and oesophageal ulceration in the context of AIDS: clinical manisfestations and preliminary report of treatment with foscarnet (phosphonoformate). Gut 1987;28:482–7.
Van Calck M, Motte S, Rickaert F, Serruys E, Adler M, Wybran J. Cryptococcal anal ulceration in a patient with AIDS. Am J Gastroenterol 1988;83:1306–8.
Erice A, Chou S, Biron KK, Stanat SC, Balfour HH, Jordan MC. Progressive disease due to ganciclovir-resistant cytomegalovirus immunocompromised patients. N Engl J med 1989;320:289–93.
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Puy-Montbrun, T., Ganansia, R., Lemarchand, N. et al. Anal ulcerations due to cytomegalovirus in patients with AIDS. Dis Colon Rectum 33, 1041–1043 (1990). https://doi.org/10.1007/BF02139221
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DOI: https://doi.org/10.1007/BF02139221