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l-DOPA treatment in Parkinson's disease: Effect on dopamine and related substances in discrete brain regions

  • Specialia
  • Pharmacologica
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Zusammenfassung

Beil-DOPA behandelten Parkinsonpatienten wird gefunden, dass Dopamin und Homovanillinsäure besonders im Striatum akkumuliert wurden. Damit wird die Möglichkeit, dass Dopamin an der Antiparkinson-Wirkung desl-DOPA entscheidend beteiligt ist, in direkter Weise gestützt.

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Author information

Authors and Affiliations

  1. Department of Psychopharmacology, Clarke Institute of Psychiatry, Canada

    L. Davidson, K. Lloyd, J. Dankova & O. Hornykiewicz

  2. Department of Pharmacology, University of Toronto, 250 College Street, Toronto 2B, Ontario, Canada

    L. Davidson, K. Lloyd, J. Dankova & O. Hornykiewicz

Authors
  1. L. Davidson
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  2. K. Lloyd
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  3. J. Dankova
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  4. O. Hornykiewicz
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Davidson, L., Lloyd, K., Dankova, J. et al. l-DOPA treatment in Parkinson's disease: Effect on dopamine and related substances in discrete brain regions. Experientia 27, 1048–1049 (1971). https://doi.org/10.1007/BF02138873

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  • DOI: https://doi.org/10.1007/BF02138873

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