Skip to main content
SpringerLink
Log in

Inhibition of angiotensin I converting enzyme and kininase in rabbit plasma by bradykinin potentiating peptide B (Pyr-Gly-Leu-Pro-Arg-Pro-Lys-Ile-Pro-Pro)

  • Specialia
  • Chimica, Biochimica, Biophysica
  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

Das Bradykinin-potenzierende Peptid B (Pyr-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro) verhindert in vitro und in vivo die Aktivität der Plasmakininase und des «converting»-Enzyms.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. S. H. Ferreira andM. Rocha e Silva, Biochem. Pharmac.11, 1123 (1962).

    Article  CAS  Google Scholar 

  2. A. J. Osbahr, J. A. Gladner andK. Laki, Biochim. biophys. Acta86, 535 (1964).

    Article  CAS  PubMed  Google Scholar 

  3. J. A. Gladner, P. A. Murtaugh, J. E. Folk andK. Laki, Ann. N.Y. Acad. Sci.104, 47 (1963).

    Article  CAS  PubMed  Google Scholar 

  4. P. N. Aarsen, Br. J. Pharmac.32, 453 (1968).

    CAS  Google Scholar 

  5. U. Hamberg, P. Ely andP. Stelwagen,Pharmacology of Hormonal Polypeptides and Proteins (Plenum Press, New York 1968), p. 626.

    Book  Google Scholar 

  6. K. Buluk andM. Malofiejew, Br. J. Pharmac.35, 79 (1969).

    Article  CAS  Google Scholar 

  7. S. H. Ferreira, Br. J. Pharmac.24, 163 (1965).

    CAS  Google Scholar 

  8. S. H. Ferreira, L. J. Greene, V. A. Alabaster, Y. S. Bakhle andJ. R. Vane, Nature225, 379 (1970).

    Article  CAS  PubMed  Google Scholar 

  9. J. W. Alken andJ. R. Vane, Nature, Lond.228, 30 (1970).

    Article  Google Scholar 

  10. J. M. Stewart, S. H. Ferreira andL. J. Greene, Biochem. Pharmac., in press (1971).

  11. H. Kato andT. Suzuki, Proc. Japan Acad.46, 176 (1970).

    Article  CAS  Google Scholar 

  12. H. Kato andT. Suzuki, Experientia26, 1205 (1970).

    Article  CAS  PubMed  Google Scholar 

  13. E. Ueda, H. Akutsu, T. Kokubu andY. Yamamura, Jap. Circulation J., in press (1971).

  14. P. T. Pickens, F. M. Bumpus, A. M. Lloyd, R. R. Smeby andL. H. Page, Circulation Res.17, 438 (1965).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Third Department of Medicine, Osaka University Hospital, Fukushima-ku, Osaka, Japan

    E. Ueda, T. Kokubu, H. Akutsu & Y. Yamamura

Authors
  1. E. Ueda
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. Kokubu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Akutsu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Y. Yamamura
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Acknowledgment. The authors wish to thank Dr. H.Kato of Institute for Protein Research, Osaka University, for his kind supply of BPP. Thanks also Dr. S.Sakakibara of Institute for Protein Research, Osaka University, for his kind supply of synthetic angiotensin I and bradykinin.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ueda, E., Kokubu, T., Akutsu, H. et al. Inhibition of angiotensin I converting enzyme and kininase in rabbit plasma by bradykinin potentiating peptide B (Pyr-Gly-Leu-Pro-Arg-Pro-Lys-Ile-Pro-Pro). Experientia 27, 1020–1021 (1971). https://doi.org/10.1007/BF02138854

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02138854

Keywords

Search

Navigation