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Serotonin, a strong inhibitor of the autocatalytic activation of trypsinogen

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Zusammenfassung

Eine Reihe von Alkylaminen wurden auf ihren hemmenden Einfluss auf die Trypsinogenaktivierung untersucht. Hierbei erwies sich Serotonin als der stärkste Hemmstoff, gefolgt von Tryptamin und Butylamin. Die Hemmung der autokatalytischen Aktivierung war bedeutend stärker ausgeprägt als die Hemmung der Aktivierung durch Enterokinase.

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Authors and Affiliations

  1. Department of Pathology, University of North Carolina School of Medicine, Chapel Hill, N.C., USA

    J. D. Geratz

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  1. J. D. Geratz
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Additional information

This study was supported by US Public Health Service grant HE-06350.

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Geratz, J.D. Serotonin, a strong inhibitor of the autocatalytic activation of trypsinogen. Experientia 21, 699–700 (1965). https://doi.org/10.1007/BF02138479

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