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Chemotaxis of leucocytes

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Summary

It is the purpose of this review to provide a survey of some more recent work on chemotaxis of leucocytes. Attention was drawn to the existence of a variety of cytotaxins (chemotactic mediators) and in particular to their cell specificity. The significance of these different cytotaxins for the accumulation of leucocytes in inflammatory sites in vivo is discussed.

Zusammenfassung

Die Aktivität chemischer Substanzen, die Wanderungsrichtung von Zellen zu bestimmen, wird als Chemotaxis bezeichnet. Chemotaxis ist von erheblichem biologischem Interesse; sie dient der Reproduktion, der Ernährung, der zellulären Organisation oder der Vermeidung schädlicher Stoffe bei Pflanzen und Tieren.

Das Referat vermittelt einen kritischen Überblick über neuere Arbeiten über Chemotaxis von Leukozyten, und es wird die Bedeutung dieses Vorganges für die entzündliche Ansammlung von Leukozyten diskutiert.

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  1. Schweizerisches Forschungsinstitut, Medizinische Abteilung, 7270, Davos-Platz, Switzerland

    H. U. Keller & E. Sorkin

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  1. H. U. Keller
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  2. E. Sorkin
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This work was supported by the Swiss National Foundation for Scientific Research, Grant No. 4518 and by the World Health Organization.

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Keller, H.U., Sorkin, E. Chemotaxis of leucocytes. Experientia 24, 641–652 (1968). https://doi.org/10.1007/BF02138287

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