Résumé
Les expériences présentées montrent que dans les noyaux isolés du thymus de rat l'inhibition de glycéraldehyde-phosphate déhydrogénase stimule la production de14CO2 de (6-14C) glucose. Un méchanisme capable d'expliquer cet effet est proposé et discuté.
References
S. Osawa, V. G. Allfrey andA. E. Mirsky, J. gen. Physiol.40, 491 (1957).
B. S. McEwen, V. G. Allfrey andA. E. Mirsky, J. biol. Chem.238, 758 (1963).
I. Betel andH. M. Klouwen, Biochim. biophys. Acta131, 453 (1967).
A. W. T. Konings, Biochim. biophys. Acta189, 125 (1969).
T. E. Conover, Arch. Biochem. Biophys.136, 541 (1970).
A. W. T. Konings, Biochim. biophys. Acta,223, 398 (1970).
B. S. McEwen, V. G. Allfrey andA. E. Mirsky, J. biol. Chem.238, 2579 (1963).
A. W. T. Konings, Experientia25, 809 (1969).
A. W. T. Konings, Life Sci.8, 1009 (1969).
H. U. Bergmeyer,Methods of Enzymatic Analysis (Academic Press, New York 1963), p. 266.
H. C. Wood, J. Katz andB. R. Landau, Biochem. Z.338, 809 (1963).
S. Sato andK. Sato, J. Biochem.56, 157 (1964).
G. Sauerman, Mh. Chem.98, 1894 (1967).
G. Sauerman, Biochim. biophys. Acta158, 1 (1968).
K. Sato, R. Suzuki andT. Tsuiki, Biochim. biophys. Acta148, 307 (1967).
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Konings, A.W.T. The influence of iodoacetate on the mechanism of nuclear glucose oxidation. Experientia 27, 253–254 (1971). https://doi.org/10.1007/BF02138128
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DOI: https://doi.org/10.1007/BF02138128