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Sulfhydryl group reagents: Effect on intestinal smooth muscle

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  • Pharmacologica
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Zusammenfassung

Die Acetylcholinkontraktion an Ratten-Jejunumstücken wird durch NEM gehemmt, was aber durch Vorbehandlung mit einem Reduktionsmittel nicht verstärkt wird. Sowohl NEM wie auch PCMB hemmen auch die Kaliumkontraktur, so dass die Hemmung der Acetylcholinkontraktion offenbar nicht auf den Rezeptor bezogen werden kann.

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Literatur

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Authors and Affiliations

  1. Department of Chemistry and Pharmaceutical Chemistry, and Department of Pharmacology, Medical College of Virginia, Health Sciences Division of Virginia Commonwealth University, 23219, Richmond, Virginia, USA

    J. F. Stubbins & P. M. Hudgins

Authors
  1. J. F. Stubbins
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  2. P. M. Hudgins
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Additional information

The present studies were supported by USPHS Grant No. NB-07273. The authors thank MissTanga Dickerson for technical assistance.

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Stubbins, J.F., Hudgins, P.M. Sulfhydryl group reagents: Effect on intestinal smooth muscle. Experientia 27, 669–670 (1971). https://doi.org/10.1007/BF02136952

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