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Widespread occurrence of inhibitors of melanoma tyrosinase in plant and mammalian tissues

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  • Chimica, Biochimica, Biophysica
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Résumé

Les inhibiteurs de tyrosinase ont été trouvés dans des extraits de foie, de rein, de rate et de cerveau de rats et de souris, ainsi que dans des tumeurs amélanotiques S91, des sérums humains, des extraits de foie, de rein, de rate, de sein, et de peau humaine. Il y a au moins deux inhibiteurs: le premier, stable à la chaleur et dialysable, tandis que le second est labile à la chaleur et non-dialysable.

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This investigation was supported by the Medical Research Council of Canada, and the Ontario Cancer Treatment and Research Foundation. One of us (H.F.H.) is a Fellow of the Ontario Cancer Treatment and Research Foundation. The authors thank Mrs.H. Li and MissE. Santos for their skilful technical assistance.

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Menon, I.A., Haberman, H.F. Widespread occurrence of inhibitors of melanoma tyrosinase in plant and mammalian tissues. Experientia 27, 644–645 (1971). https://doi.org/10.1007/BF02136936

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  • DOI: https://doi.org/10.1007/BF02136936

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