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Mechanism of non-disjunction of meiotic chromosomes and of degeneration of maturation spindles in eggs affected by intrafollicular overripeness

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Résumé

La dégénérescence des fibres en fuseau est proposée comme un facteur responsable de la non-disjonction des chromosomes méiotiques. Cette hypothèse est basée sur l'observation, dans les œufs affectés par l'hypermaturité intrafolliculaire, de positions chromosomiques anormales pendant les métaphases méiotiques et de changements dégénératifs dans les fuseaux méiotiques.

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References

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Authors and Affiliations

  1. Laboratoire d'Hormonologie et d'Embryologie, Clinique Universitaire de Gynécologie et d'Obstétrique, 1211, Genève 4, Switzerland

    K. Mikamo

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  1. K. Mikamo
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Additional information

The author wishes to express his thanks to Prof.E. Witschi, the Population Council, Bio-Medical Division, the Rockefeller University, for critical reading of the manuscript. This study was supported by the Ford Foundation Population Program, Grant No. 64-411.

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Mikamo, K. Mechanism of non-disjunction of meiotic chromosomes and of degeneration of maturation spindles in eggs affected by intrafollicular overripeness. Experientia 24, 75–78 (1968). https://doi.org/10.1007/BF02136806

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  • DOI: https://doi.org/10.1007/BF02136806

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