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Hydrolysis of DHEA sulphate after oral application

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  • Endocrinologica
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Zusammenfassung

Nach oraler Gabe von 4-14C-DHEA und Na-7α-3H-DHEA-sulfat liessen sich mittels einer Duodenalsonde 91 ml Duodenalsaft innerhalb von 45 min gewinnen, aus denen man u.a.3H-markierte, freie 17-Ketosteroide isolierte. Anhand der Ausbeute an 4-14C-DHEA konnte eine zumindest 10% betragende Hydrolyse verabreichten DHEA-sulfats nachgewiesen werden.

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References

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Authors and Affiliations

  1. Abteilung für Experimentelle Endokrinologie Universitäts-Frauenklinik, 65 Mainz, Germany

    G. W. Oertel & P. Knapstein

Authors
  1. G. W. Oertel
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  2. P. Knapstein
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Oertel, G.W., Knapstein, P. Hydrolysis of DHEA sulphate after oral application. Experientia 24, 73–74 (1968). https://doi.org/10.1007/BF02136804

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  • DOI: https://doi.org/10.1007/BF02136804

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