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Effects of various inhibitors of protein cross-linking on the formation of fertilization membrane in sea urchin egg

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  • Pharmacologica
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Résumé

La stabilization de la membrane de fécondation de l'œuf de l'OursinParacentrotus lividus est inhibée par la pénicillamine, l'isoniazide, les hydrazines benzylique et benzoïque et la semicarbazide. Les effets de ces substances sont interprétés sur la base de leur action inhibitrice sur la formation de certaines liaisons transversales intermoléculaires. Ces liaisons pourraient impliquer, comme chez le collagène et l'élastine, des groupes aldéhydes associés entre eux par condensation de type aldol ou avec de groupes aminés avec formation de base de Schiff.

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  1. Station Zoologique, F-06, Villefranche-sur-Mer, France

    R. Lallier

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  1. R. Lallier
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Lallier, R. Effects of various inhibitors of protein cross-linking on the formation of fertilization membrane in sea urchin egg. Experientia 27, 1323–1324 (1971). https://doi.org/10.1007/BF02136716

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  • DOI: https://doi.org/10.1007/BF02136716

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