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Effect of heat on serum thyroxin and thyrotropin and its modification by dihydrotachysterol

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  • Physiologica
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Zusammenfassung

Dehydrotachysterol (DHT 500 µg/kg/24 h) erhöht den TSH- und T-4-Spiegel in Rattenserum bei normalen und hohen Temperaturen, ohne den Calcium-Spiegel zu verändern, und verhindert den Tod von Ratten, die bei 34° oder 37°C gehalten werden. Das Überleben der Ratten nach DHT-Injektionen erklärt sich durch erhöhte T-4-Produktion, die einen negativen «Feedback» auf den Hypothalamus ausübt und so die lethale Überproduktion von TSH verhindert.

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Literatur

  1. E. Tal andF. G. Sulman, Neuroendocrinology, in press (1971).

  2. J. M. McKenzie, Endocrinology62, 865 (1958).

    Article  CAS  Google Scholar 

  3. B. E. P. Murphy, C. F. Pattee andA. Gold, J. clin. Endocrin.26, 247 (1966).

    Article  CAS  Google Scholar 

  4. S. Djojosoebagio andS. Turner, Proc. Soc. exp. Biol. Med.116, 1099 (1964).

    Article  CAS  Google Scholar 

  5. L. Balogh, S. Donhoffer, G. Mertyan, T. Pap andJ. Toth, Acta physiol. hung.82, 103 (1952).

    Google Scholar 

  6. E. Bajusz,Physiology and Pathology of Adaptation Mechanisms, Pergamon Press, New York (1969), p. 447.

    Google Scholar 

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Authors and Affiliations

  1. Department of Applied Pharmacology, School of Pharmacy, Hebrew University, Jerusalem, Israel

    E. Tal, E. Superstine & G. G. Sulman

Authors
  1. E. Tal
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  2. E. Superstine
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  3. G. G. Sulman
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Additional information

This study was generously aided by a grant from the Dr.Gerald Kaplan family, Kfar Shmaryahu (Israel).

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Tal, E., Superstine, E. & Sulman, G.G. Effect of heat on serum thyroxin and thyrotropin and its modification by dihydrotachysterol. Experientia 27, 1299–1300 (1971). https://doi.org/10.1007/BF02136699

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  • DOI: https://doi.org/10.1007/BF02136699

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