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Chromaffin granules: Effects of ions and ATP on catecholamine content, ATPase activity, and membrane phosphorylation

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  • Chimica, Biochimica, Biophysica
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Résumé

L'ATP induit la libération de catécholamines des granules chromaffines médullaires. Nous discutons le rôle du Cl− dans ce processus vis-à-vis l'activité de l'ATPase et la phosphorylation des membranes. Nos résultats indiquent que la réaction aboutissant à la liberation de catécholamines est un phenomène comportant plusieurs étapes échelonnées après l'hydrolyse de l'ATP.

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Authors and Affiliations

  1. Department of Pharmacology and Therapeutics, McGill University, 3655 Drummond Street, Montreal 109, Québéc, Canada

    J. Dworkind & J. M. Trifaró

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  1. J. Dworkind
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  2. J. M. Trifaró
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Supported by the Medical Research Council of Canada.

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Dworkind, J., Trifaró, J.M. Chromaffin granules: Effects of ions and ATP on catecholamine content, ATPase activity, and membrane phosphorylation. Experientia 27, 1277–1279 (1971). https://doi.org/10.1007/BF02136684

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  • DOI: https://doi.org/10.1007/BF02136684

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