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The effect of ethionine on the increased metabolism of some drugs and increased urinary excretion of vitamin C induced by pretreatment with chloretone or phenobarbital

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Riassunto

L'etionina è capace di inibire l'aumentata attività metabolica del fegato sul pentobarbital e sul meprobamato indotta da un pretrattamento con fenobarbital o cloretone. Essa invece non inibisce l'induzione dell'aumento dell'eliminazione urinaria di vitamina C causata da un analoge prettamento con fenobarbital o clorotone. Si conclude che i meccanismi delle due induzioni non possono considerarsi identici.

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Authors and Affiliations

  1. Istituto di Farmacologia e di Terapia, Università degli Studi, Milano, Italy

    R. Kato, P. Vassanelli & G. Frontino

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  1. R. Kato
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  2. P. Vassanelli
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  3. G. Frontino
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Kato, R., Vassanelli, P. & Frontino, G. The effect of ethionine on the increased metabolism of some drugs and increased urinary excretion of vitamin C induced by pretreatment with chloretone or phenobarbital. Experientia 18, 9–10 (1962). https://doi.org/10.1007/BF02136628

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