Zusammenfassung
Neoplastische Mausmastzellen des Stammes P815Y wurden auf lange Dauer im Chemostaten gezüchtet. Solche Versuche, in denen es erstmals gelang, stabile stationäre Zustände des Zellkulturenwachstums auch bei sehr kleinen Durchfluss- bzw. Verdünnungskonstanten zu erzeugen, werden eingehend beschrieben.
Literatur
J. Monod, Annls Inst. Pasteur79, 390 (1950).
A. Novick andL. Szilard, Science112, 715 (1950).
A. Novick andL. Szilard, Proc. natn Acad. Sci. USA36, 708 (1950).
D. Herbert, R. Elsworth, andR. C. Telling, J. gen. Microbiol.14, 601 (1956).
H. Moser, Cold Spring Harb. Symp. quant. Biol.22, 121 (1957).
H. Moser, Carnegie Institution of Washington Publication 614, Washington, D.C. (1958).
D. Herbert, inRecent Progress in Microbiology, 8th Intern. Congress Microbiol., Stockholm (Almquist and Wiksells, 1958).
D. E. Contois, J. gen. Microbiol.21, 40 (1959).
E. P. Cohen andH. Eagle, J. exp. Med.113, 467 (1961).
K. MacCarthy andS. Graff, Cancer Res.18, 741 (1958).
Manufactured by Chemapec Inc., 1 Newark Street, Hoboken, N.J. 07030, USA.
G. A. Fischer andA. C. Sartorelli, Meth. med. Res.10, 247 (1964).
C. C. Spicer, Biometrics11, 225 (1955).
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This investigation was supported by the Office of Naval Research under contract No. Nonr-266(76) and by the Health Research Council of the City of New York under contract No. I-428, and was carried out at Columbia University (Department of Biochemistry).
Recipient of Career Scientist Award of the Health Research Council of the City of New York under Contract No. I-428.
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Moser, H., Vecchio, G. The production of stable steady-states in mouse ascites mast cell cultures maintained in the chemostat. Experientia 23, 120–123 (1967). https://doi.org/10.1007/BF02135954
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DOI: https://doi.org/10.1007/BF02135954