Zusammenfassung
Menschliche Leukozyten, die vorher 2 resp. 4 h der Wirkung von Colcemid ausgesetzt worden waren, ergaben in Zellkulturen 45 resp. über 50% Zellen mit 45 oder weniger Chromosomen im Vergleich zu 10% in Kontrollkulturen ohne Colcemid.
References
R. G. Kleinfield andJ. E. Sisken, J. Cell Biol.31, 369 (1966).
M. E. Romsdahl, Expl Cell Res.50, 463 (1968).
E. Stubblefield, R. Kleveez, Expl. Cell Res.40, 660 (1965).
N. P. Bishun, W. R. M. Morton, B. McLaverty, Lancet2, 315 (1964).
H. Kato, T. H. Yosida, Expl Cell Res.60, 459 (1970).
B. Hereros, A. Guerro, E. Romo, Lancet11 499 (1966).
E. Stubblefield, E. Kleveez, L. Deaven, J. Cell Physiol.69, 345 (1967).
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This work is supported financially by Schering Chemicals Ltd., Burgess Hill, Sussex. We would like to thank Dr.A. G. Pitchford for advice and MissE. Gristwood for technical assistance.
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Bishun, N., Mills, J. & Williams, D. Induction of chromosome abnormalities by reversal of colcemid inhibition in leucocyte cultures. Experientia 27, 943–944 (1971). https://doi.org/10.1007/BF02135761
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DOI: https://doi.org/10.1007/BF02135761