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Relationship between Rm values and biological activity of steroid esters

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  • Pharmacologia
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Riassunto

I valori Rm di una serie di esteri del testosterone sono stati determinati con un metodo cromatografico su strato sottile a fasi invertite. Si è dimostrata una relazione lineare fra i valori Rm, espressione del carattere lipofilo delle molecole, e il protrarsi dell'attività degli stessi esteri del testosterone. Si conclude che i valori cromatografici Rm possono essere utili nello studio delle relazioni fra struttura e attività.

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Biagi, G.L., Barbaro, A.M. & Guerra, M.C. Relationship between Rm values and biological activity of steroid esters. Experientia 27, 918–919 (1971). https://doi.org/10.1007/BF02135743

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