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Action of reserpine and imipramine on intracellular storage of 5-hydroxytryptamine in blood platelets

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Zusammenfassung

In isolierten Blutplättchen von Katzen vermindert Imipramin im Gegensatz zu Reserpin das endogene 5-Hydroxytryptamin (5HT) und die 5HT-Speicherorganellen nicht wesentlich, obwohl es wie Reserpin die Aufnahme von exogenem 5HT herabsetzt. Hemmung des Membrantransportes von 5HT durch Imipramin scheint also das intrazellulär gespeicherte 5HT nur relativ wenig zu beeinflussen.

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Literatur

  1. F. B. Hughes andB. B. Brodie, J. Pharmac. exp. Ther.127, 96 (1959).

    CAS  Google Scholar 

  2. A. Pletscher, W. P. Burkard, J. P. Tranzer andK. F. Gey, Life Sci.6, 273 (1967).

    Article  CAS  Google Scholar 

  3. J. P. Tranzer, M. Da Prada andA. Pletscher, Nature212, 1574 (1966).

    Article  CAS  Google Scholar 

  4. G. Bartholini, A. Pletscher andK. F. Gey, Experientia17, 541 (1961).

    Article  CAS  Google Scholar 

  5. D. F. Bogdanski, A. Pletscher, B. B. Brodie andS. Udenfriend, J. Pharmac. exp. Ther.117, 82 (1956).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Medizinische Forschungsabteilung der F. Hoffmann-La Roche & Co. AG, Basel, Switzerland

    A. Pletscher & J. P. Tranzer

Authors
  1. A. Pletscher
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  2. J. P. Tranzer
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Pletscher, A., Tranzer, J.P. Action of reserpine and imipramine on intracellular storage of 5-hydroxytryptamine in blood platelets. Experientia 23, 289–291 (1967). https://doi.org/10.1007/BF02135693

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