Skip to main content
SpringerLink
Log in

Enhancement of fibrinolysis and thrombolysis by polysorbate 80 (Tween 80®)

  • Specialia
  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

Polysorbate 80 (Tween 80®), eine polyhydroxyle, nicht-ionisierbare, oberflächenaktive Substanz, vermindert die Adsorption von Urokinase an Glas, erhöht deren fibrinolytische Aktivität in vitro und steigert ihre thrombolytische Wirkung in experimentell hervorgerufenen Thrombosen im Kaninchen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. T. Astrup andS. Müllertz, Archs Biochem. Biophys.40, 346 (1952).

    Article  CAS  Google Scholar 

  2. K. N. von Kaulla, inChemistry of Thrombolysis: Human Fibrinolytic Enzymes (Charles C. Thomas, Springfield, Illinois 1963), p. 261.

    Google Scholar 

  3. T. Astrup andN. Alkjaersig, Nature168, 565 (1951).

    Article  CAS  Google Scholar 

  4. M. N. Richard andB. E. Sanders, Can. J. Biochem. Physiol.41, 211 (1963).

    Article  CAS  Google Scholar 

  5. P. Brakman, P. Klug andT. Astrup, Thromb. Diath. haemorrh.11, 234 (1964).

    CAS  Google Scholar 

  6. M. Lassen, Scand. J. clin. Lab. Invest.10, 384 (1958).

    Article  CAS  Google Scholar 

  7. K. Magnus, J. Guld, H. Waaler andM. Magnusson, Am. Rev. Tuberc. pulm. Dis.74, 297 (1956).

    CAS  Google Scholar 

  8. H. Waaler, J. Guld, K. Magnus andM. Magnusson, Bull. Wld Hlth Org.19, 783 (1958).

    CAS  Google Scholar 

  9. Ch. H. Lack andS. Y. Ali, Nature201, 1030 (1964).

    Article  CAS  Google Scholar 

  10. E. E. Cliffton andA. R. Burchell, Thromb. Diath. haemorrh.5, 463 (1961).

    CAS  Google Scholar 

  11. H. C. Kwaan andT. Astrup, Circulation Res.17, 477 (1965).

    Article  CAS  Google Scholar 

  12. N. Back, A. E. Munson, B. R. Munson, H. B. Lassman, C. M. Ambrus andJ. L. Ambrus, Fedn Proc. Fedn Am. Socs exp. Biol.24, Abstract No. 1432, 387 (1965).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The James F. Mitchell Foundation, Institute for Medical Research, 20015, Washington D.C., USA

    H. C. Kwaan, P. Brakman & T. Astrup

Authors
  1. H. C. Kwaan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Brakman
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. Astrup
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This work was supported by GrantsNos. HE-05020 and HE-7804 from the National Institutes of Health, National Heart Institute. The address of Dr.Kwaan is now: Northwestern University, Department of Medicine, Chicago (Illinois, USA).

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kwaan, H.C., Brakman, P. & Astrup, T. Enhancement of fibrinolysis and thrombolysis by polysorbate 80 (Tween 80®). Experientia 23, 261–262 (1967). https://doi.org/10.1007/BF02135671

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02135671

Keywords

Search

Navigation