Experientia

, Volume 20, Issue 4, pp 178–190 | Cite as

Mineralhaushalt und hormonale Aktivität im Winterschlaf

  • Paul Raths
Übersichtsreferate

Summary

A review is presented on the metabolism of sodium, potassium, calcium and magnesium during natural hibernation in mammals, and its relation to endocrine activity. With the entrance into hibernation, a change of homeostasis and an initial vagoinsular stage occur, resulting for instance in a hyperpotassemia. When the body temperature falls further, a sympathicoadrenal stage is observed whilst the serum potassium attains its normal level, probably favoured by simultaneous activation of the zona glomerulosa. Most animals show an increase of serum calcium and magnesium in hibernation in consequence of anhydremia, as well as of probably parathyreoid activity. It is suggested that an aldosterone and/or ADH secretion is provoked by diminishing of the intravasal space in deep hibernation. The mineral metabolism of bats differs in several points from that of other hibernators.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    O. A. M. Wyss, Pflügers Arch. ges. Physiol.229, 599 (1932).CrossRefGoogle Scholar
  2. 2.
    R. S. Person, Trudy instit. morphol. zhivotnich im. Severtsova6, 173 (1952).Google Scholar
  3. 3.
    M. L. Riedesel undG. E. Folk, Amer. Naturalist92, 307 (1958).CrossRefGoogle Scholar
  4. 4.
    P. Raths, Z. Biol.113, 173 (1962).PubMedGoogle Scholar
  5. 5.
    A. Denyes undJ. Hassett, Bull. Mus. Comp. Zool. Harvard Univ.124, 437 (1960).Google Scholar
  6. 6.
    G. Biörck, B. Johansson undS. Veige, Acta physiol. scand.37, 281 (1956).CrossRefPubMedGoogle Scholar
  7. 7.
    P. Suomalainen, Triangel2, 228 (1956).Google Scholar
  8. 8.
    E. Klar, Z. exp. Med.104, 105 (1938).CrossRefGoogle Scholar
  9. 9.
    G. B. Forbes, inC. L. Comar undF. Bronner,Mineral Metabolism, vol. 2, part B (New York, London 1962), p. 1.Google Scholar
  10. 10.
    E. Eliassen undH. Leivestad, Nature (Lond.)192, 459 (1961).CrossRefPubMedGoogle Scholar
  11. 11.
    J. J. Christian, Science134, 390 (1961).CrossRefPubMedGoogle Scholar
  12. 12.
    J. E. McBirnie, F. G. Pearson, G. A. Trusler, H. H. Karachi undW. G. Bigelow, Canad. J. Med. Sci.31, 421 (1953).Google Scholar
  13. 13.
    P. Suomalainen, Sitzber. Finn. Akad. Wiss.1953, 131 (1954).Google Scholar
  14. 14.
    D. Ferdmann undO. Feinschmidt, Erg. Biol.8, 1 (1932).Google Scholar
  15. 15.
    E. A. Pora, F. Stoicovici undD. J. Rosca, Stud. ceret. biol. (Cluj)11, 363 (1960).Google Scholar
  16. 16.
    B. Nordgren, Acta physiol. scand.58, Suppl. 202 (1963).Google Scholar
  17. 17.
    F. A. Carone undR. S. Cooke, Amer. J. Physiol.172, 684 (1953).PubMedGoogle Scholar
  18. 18.
    S. R. Hong, Amer. J. Physiol.188, 137 (1957).PubMedGoogle Scholar
  19. 19.
    M. L. Zimny undC. Bourgeois, J. cell. comp. Physiol.56, 93 (1960).CrossRefPubMedGoogle Scholar
  20. 20.
    H. Nagai, Z. allg. Physiol.9, 243 (1909).Google Scholar
  21. 21.
    T. M. Carpenter, J. biol. Chem.122, 343 (1937/38).Google Scholar
  22. 22.
    C. Albers, W. Brendel, A. Hardewig undW. Usinger, Pflügers Arch. ges. Physiol.266, 373 (1958).CrossRefGoogle Scholar
  23. 23.
    W. v. Buddenbrock,Vergleichende Physiologie, vol. 3 (Basel 1956).Google Scholar
  24. 24.
    M. B. Lipsett, I. L. Schwartz undN. A. Thorn, inC. L. Comar undF. Bronner,Mineral Metabolism, vol. 1, part B (New York, London 1961) p. 473.Google Scholar
  25. 25.
    A. Denyes undR. H. Horwood, Canad. J. Biochem. Physiol.38, 1479 (1960).CrossRefPubMedGoogle Scholar
  26. 26.
    Ch. Kayser undJ. Schwartz, C. R. Soc. Biol. Paris154, 778 (1960).Google Scholar
  27. 27.
    V. Popovic, Bull. Mus. Comp. Zool. Harvard Univ.124, 105 (1960).Google Scholar
  28. 28.
    Ch. Kayser undA. Petrovic, C. R. Soc. Biol. Paris156, 501 (1962).PubMedGoogle Scholar
  29. 29.
    Ch. Kayser undM. Aron, C. R. Soc. Biol. Paris129, 225 (1938).Google Scholar
  30. 30.
    H. W. Deane undCh. P. Lyman, Endocrinology55, 300 (1954).CrossRefPubMedGoogle Scholar
  31. 31.
    P. Raths undW. Schulze, Z. Biol.109, 233 (1957).PubMedGoogle Scholar
  32. 32.
    W. N. Holmes, Endocrinology57, 409 (1955).CrossRefPubMedGoogle Scholar
  33. 33.
    R. Poche, Z. Zellforsch.50, 332 (1959).CrossRefPubMedGoogle Scholar
  34. 34.
    R. Engel, P. Raths undW. Schulze, Z. Biol.109, 381 (1957).PubMedGoogle Scholar
  35. 35.
    Ch. Kayser, Arch. Sci. Physiol.15, 377 (1961).Google Scholar
  36. 36.
    Ch. Kayser undA. Petrovic, C. R. Soc. Biol. Paris152, 519 (1958).PubMedGoogle Scholar
  37. 37.
    G. Farrell undA. N. Taylor, Ann. Rev. Physiol.24, 471 (1962).CrossRefGoogle Scholar
  38. 38.
    C. Fortier, Ann. Rev. Physiol.24, 223 (1962).CrossRefGoogle Scholar
  39. 39.
    P. Raths, Zool. Anzeiger159, 139 (1957).Google Scholar
  40. 40.
    F. C. Kallen, Bull. Mus. Comp. Zool. Harvard Univ.124, 373 (1960); Amer. J. Physiol.198, 999 (1960).Google Scholar
  41. 41.
    T. Pengelley undK. C. Fisher, Canad. J. Zool.39, 105 (1961).CrossRefGoogle Scholar
  42. 42.
    Ch. P. Lyman undR. C. O'Brien, Bull. Mus. Comp. Zool. Harvard Univ.124, 353 (1960).Google Scholar
  43. 43.
    G. Azzali, Acta neurovegetat.10, 402 (1954).Google Scholar
  44. 44.
    P. Suomalainen undP. Nyholm, B. Hanström Zool. Papers, 20. Nov. 1956, 269.Google Scholar
  45. 45.
    E. Flückiger undF. Verzár, Helv. physiol. Acta15, 293, 304 (1957).Google Scholar
  46. 46.
    W. S. Wilde, inC. L. Comar undF. Bronner,Mineral Metabolism, vol. 2, part B (New York-London 1962), p. 73.Google Scholar
  47. 47.
    P. Raths, Z. Biol.112, 282 (1961).PubMedGoogle Scholar
  48. 48.
    Ch. P. Lyman undE. H. Leduc, J. cell. comp. Physiol.41, 471 (1953).CrossRefGoogle Scholar
  49. 49.
    C. L. Dodgen undF. R. Blood, Amer. J. Physiol.187, 151 (1956).PubMedGoogle Scholar
  50. 50.
    P. Suomalainen, Sitzber. Finn. Akad. Wiss.1943, 163 (1944).Google Scholar
  51. 51.
    J. Odar, Z. Zellforsch.41, 351 (1955).CrossRefPubMedGoogle Scholar
  52. 52.
    C. Aron undCh. Kayser, C.R. Soc. Biol. Paris150, 410 (1956).PubMedGoogle Scholar
  53. 53.
    H. J. Portius undP. Raths, Z. Biol.109, 287 (1957).Google Scholar
  54. 54.
    R. Agid undV. Popovic, J. Physiol. (Paris)49, 7 (1957).Google Scholar
  55. 55.
    H. Pohl, Z. vgl. Physiol.145, 109 (1961).CrossRefGoogle Scholar
  56. 56.
    Ch. Kayser,The Physiology of Natural Hibernation (Pergamon Press, 1961).Google Scholar
  57. 57.
    P. Suomalainen, Bull. Mus. Comp. Zool. Harvard Univ.124, 271 (1960).Google Scholar
  58. 58.
    P. Suomalainen, Skand. Arch. Physiol.78, 272 (1938).CrossRefGoogle Scholar
  59. 59.
    A. G. Kratinov, V. V. Morina, I. S. Reshetnikova undE. A. Torbina, Dokl. akad. nauk SSSR, biol. Ser.2, 259 (1947).Google Scholar
  60. 60.
    L. Zizine, C. R. Akad. Sci. Paris242, 681 (1956).Google Scholar
  61. 61.
    P. Haberey, R. Bidetel, C. Spach undCh. Kayser, C.R. Soc. Biol. Paris154, 780, 1870 (1960).PubMedGoogle Scholar
  62. 62.
    L. Zirm, Z. Naturforsch.11, 530 (1956).Google Scholar
  63. 63.
    P. Suomalainen undH.-M. Herlevi, Science114, 300 (1951); Arch. Soc. ‘Vanamo’1951, 72.CrossRefPubMedGoogle Scholar
  64. 64.
    H. Selye undP. S. Timiras, Nature (Lond.)164, 745 (1949).CrossRefGoogle Scholar
  65. 65.
    Z. Vlašin undJ. Filkuka, Arch. exp. Path. Pharmakol.227, 414 (1956).CrossRefGoogle Scholar
  66. 66.
    B. A. Houssay,Human Physiology (New York, Toronto, London 1955).Google Scholar
  67. 67.
    A. König, H. Lahmann, W. Rautenberg undR. Sobanski, Pflügers Arch. ges. Physiol.273, 120 (1961).CrossRefGoogle Scholar
  68. 68.
    E. Bülbring, inAdrenergic Mechanisms (CIBA Found. Symp., London 1960), p. 275.Google Scholar
  69. 69.
    J. P. Hannon undA. M. Larson, Amer. J. Physiol.203, 1055 (1962).PubMedGoogle Scholar
  70. 70.
    J. P. Hannon, Science and Industry3, Teil 3, 469 (1963).Google Scholar
  71. 71.
    P. Suomalainen, Biochem. Z.295, 145 (1938).Google Scholar
  72. 72.
    P. Suomalainen undV. J. Uuspää, Nature (Lond.)182, 1500 (1958).CrossRefGoogle Scholar
  73. 73.
    X. J. Musacchia, M. Jellinek undT. Cooper, Proc. Soc. exp. Biol. Med.110, 856 (1956).CrossRefGoogle Scholar
  74. 74.
    F. Strumwasser, Amer. J. Physiol.196, 15, 23 (1959).PubMedGoogle Scholar
  75. 75.
    W. W. Sadler undW. S. Tyler, Acta endocrin.39, 586, 597 (1960).Google Scholar
  76. 76.
    O. Eränkö, Acta endocrin.18, 174 (1955).Google Scholar
  77. 77.
    M. L. Riedesel undG. E. Folk, Amer. J. Physiol.179, 665 (1954).Google Scholar
  78. 78.
    M. L. Riedesel undG. E. Folk, J. Mammalogy38, 423 (1957).CrossRefGoogle Scholar
  79. 79.
    P. Suomalainen, Annal. Acad. Sci. Fenn. Ser. A.53, 1 (1939).Google Scholar
  80. 80.
    M. L. Riedesel, Bull. Mus. Comp. Zool. Harvard Univ.124, 421 (1960).Google Scholar
  81. 81.
    F. C. McLean, inC. L. Comar undF. Bronner Mineral Metabolism, vol. 1, part A (New York-London 1960), p. 1.Google Scholar
  82. 82.
    W. S. Platner undM. J. Hosko, Amer. J. Physiol.174, 273 (1953).PubMedGoogle Scholar
  83. 83.
    A. Nitschke, Z. exp. Med.82, 227 (1932).CrossRefGoogle Scholar
  84. 84.
    A. Nitschke undE. Maier, Z. exp. Med.82, 215 (1932).CrossRefGoogle Scholar
  85. 85.
    G. Ackermann, Z. exp. Med.102, 747 (1938).CrossRefGoogle Scholar
  86. 86.
    St. Skowron undSt. Zajaczek, C. R. Soc. Biol. Paris141, 1105 (1947).Google Scholar
  87. 87.
    Ch. Kayser, A. Petrovic undA. Porte, C. R. Soc. Biol. Paris155, 2178 (1961).Google Scholar
  88. 88.
    A. Porte, Ch. Kayser, A. Petrovic undM. E. Stoeckel, C. R. Soc. Biol. Paris157, 370 (1963).PubMedGoogle Scholar
  89. 89.
    P. L. Munson, Ph. F. Hirsch undA. H. Tashjian Jr., Ann. Rev. Physiol.25, 325 (1963).CrossRefGoogle Scholar
  90. 90.
    M. A. Brock, Amer. J. Physiol.199, 195 (1960).PubMedGoogle Scholar
  91. 91.
    R. Kristoffersson, Annal. Acad. Sci. Fenn. Ser. A IV Biologica50, 1 (1961).Google Scholar
  92. 92.
    J. K. Aikawa, Proc. Soc. exp. Biol. Med.103, 363 (1960).CrossRefGoogle Scholar

Copyright information

© Birkhäuser Verlag 1964

Authors and Affiliations

  • Paul Raths
    • 1
  1. 1.Physiologisches Institut der Martin-Luther-Universität Halle a. d. S.DDR

Personalised recommendations