Abstract
It is a matter of discussion in literature, if autoimmunological processes are involved in the pathogenesis of primary open angle glaucoma. Therefore we determined circulating C1q binding immune complexes, collagen antibodies, antinuclear antibodies and anti-nDNA-antibodies in the sera of patients with this disease. The result of our investigation and of recent papers lead to the conclusion that autoimmunological processes are not involved in the pathogenesis of primary open angle glaucoma.
Zusammenfassung
Es ist Gegenstand der Diskussion in der Literatur, ob autoimmunologische Prozesse bei der Entstehung des primären Offenwinkelglaukoms beteiligt sind. Wir untersuchten daher im Serum von Patienten mit dieser Erkrankung zirkulierende C1q-bindende Immunkomplexe, Kollagenantikörper, anti-nukleäre Antikörper und anti-nDNA-Antikörper. Das Ergebnis unserer Studie und anderer neuerer Arbeiten läßt den Schluß zu, daß autoimmunologische Prozesse bei der Entstehung des primären Offenwinkelglaukoms nicht beteiligt sind.
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Radda, T.M., Menzel, J., Drobec, P. et al. Immunologische Untersuchungen beim primären Offenwinkelglaukom. Graefe's Arch Clin Exp Ophthalmol 218, 55–57 (1982). https://doi.org/10.1007/BF02134104
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DOI: https://doi.org/10.1007/BF02134104