Skip to main content
Log in

Chemotherapy for advanced and/or recurrent cervical cancer

  • Originals
  • Published:
Archives of gynecology Aims and scope Submit manuscript

Summary

A combination of bleomycin, vincristine, mitomycin-C, and cisplatin was used to treat 39 patients with advanced and/or recurrent cervical cancer. Twenty patients showed an objective response (complete or partial) with a mean duration of 14.8 months. The overall response rate was 58.8%. Twelve patients are still alive and in remission 7–36 months after the start of chemotherapy. Toxicity was acceptable.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Alberts DS, Martimbeau PW, Surwit EA, Oishi N (1981) Mitomycin-C, bleomycin, vincristine, and cis-platinum in the treatment of advanced, recurrent squamous cell carcinoma of the cervix. Cancer Clin Trials 4:313–316

    PubMed  Google Scholar 

  2. Belinson JL, Stewart JA, Richards AL, McClue M (1985) Bleomycin, vincristine, mitomycin-C and cisplatin in the management of gynecological squamous cell carcinomas. Gynecol Oncol 20:387–393

    PubMed  Google Scholar 

  3. Forney JP, Morrow CP, Di Saia PJ, Futoran RJ (1975) Seven — drug polychemotherapy in the treatment of advanced and recurrent squamous carcinoma of the female genital tract. Am J Obstet Gynecol 123:748–752

    PubMed  Google Scholar 

  4. Freedman RS, Herson J, Wharton JT, Rutledge FN (1980) Single-agent chemotherapy for recurrent carcinoma of the cervix. Cancer Clin Trials 3:345–350

    PubMed  Google Scholar 

  5. Piver MS, Barlow JJ, Lele SB, Maniccia M (1984) Weekly cis-diamminedichloroplatinum II as induction chemotherapy in recurrent carcinoma of the cervix. Gynecol Oncol 18: 313–319

    PubMed  Google Scholar 

  6. Thigpen T, Vance RB, Balducci L, Blessing J (1981) Chemotherapy in the management of advanced or recurrent cervical and endometrial carcinoma. Cancer 48:658–665

    PubMed  Google Scholar 

  7. Tropé C, Johnsson JE, Simonsen E, Sigurdsson K, Stendahl U, Mattsson W, Gullberg B (1983) Bleomycin — mitomicin-C in advanced carcinoma of the cervix. A third look. Cancer: 591–593

  8. Wheelock JB, Krebs HB, Goplerud DR, Myers M (1985) Cis-Platinum, doxorubicin and methotrexate treatment for recurrent cervical cancer. Obstet Gynecol 66: 410–412

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lahousen, M., Pickel, H. & Tamussino, K. Chemotherapy for advanced and/or recurrent cervical cancer. Arch. Gynecol. 240, 247–252 (1987). https://doi.org/10.1007/BF02134075

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02134075

Key words

Navigation