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Instant effect of induced abortion on serum ceruloplasmin activity, copper and zinc levels

Archives of gynecology volume 240, pages 21–25 (1987)Cite this article

Summary

Serum ceruloplasmin activity, serum copper and zinc levels were determined in 20 patients aged 19–43 with normal pregnancies of first trimester (5–9 weeks) admitted to hospital for legal abortion. Blood samples were taken from each patient 30 min before and 3 h after induced abortion. Significantly reduced ceruloplasmin activity (P < 0.01) and serum copper level (P < 0.05) were observed following induced abortion while zinc level didn't demonstrate any significant change (P > 0.05). A high degree of correlation was observed between the ceruloplasmin activity and the serum copper level (r = 0.87). Ceruloplasmin activity and serum copper values seem to be an index of feto-placental function in early pregnancy.

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Affiliations

  1. Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey

    Hilal Özgüneş & Suna Duru

  2. Department of Obstetrics and Gynaecology, Hacettepe University, Ankara, Turkey

    M. Sinan Beksaç

  3. Department of Public Health, Hacettepe University, Ankara, Turkey

    Kadriye Kayakirilmaz

Authors
  1. Hilal Özgüneş
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  2. M. Sinan Beksaç
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  3. Suna Duru
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  4. Kadriye Kayakirilmaz
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Özgüneş, H., Sinan Beksaç, M., Duru, S. et al. Instant effect of induced abortion on serum ceruloplasmin activity, copper and zinc levels. Arch. Gynecol. 240, 21–25 (1987). https://doi.org/10.1007/BF02134060

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  • DOI: https://doi.org/10.1007/BF02134060

Key words

  • Ceruloplasmin activity
  • Copper
  • Zinc
  • Induced abortion
  • First trimester
  • Feto-placental function