Abstract
Vitreous fluorophotometry was performed on 29 normal individuals to evaluate the state of the blood-retinal barrier with respect to age, blood pressure, and serum glucose. Fluorescein leakage into the vitreous was found in the absence of any disease. This leakage increased with increasing age and was minimally related to blood pressure and not at all affected by serum glucose or serum creatinine.
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Brande LS, Cunha-Vaz JG, Goldberg MF, Frenkel M, Hughes JR (1981) A new approach for diagnosing retrobulbar neuritis with the use of vitreous fluorophotometry. Invest Ophthalmol Vis Sci (Suppl) 20:59
Cunha-Vaz JG, Faria de Abreu JR, Campos AJ, Figo J (1975) Early breakdown of the blood retinal barrier in diabetes. Br J Ophthalmol 59:649–656
Dutton JJ, Krupin T, Waltman SR, Koloms BA, Becker B (1980) Fluorophotometry and the blood ocular barrier in experimental systemic hypertension. Arch Ophthalmol 98:731–733
Fishman GA, Cunha-Vaz J, Salazaro T (1981) Vitreous fluorophotometry in patients with retinitis pigmentosa. Arch Ophathalmol 99:1202–1207
Jampol M, White S, Cuhna-Vaz J (1981) Vitreous fluorophotometry in patients with hypertension. Invest Ophthal Vis Sci (Suppl) 20:11
Waltman SR, Oestrich C, Krupin T, Hanish S, Ratzan S, Kilo C, Becker B (1978) Quantitative vitreous fluorophotometry: a sensitive technique for measuring early breakdown of the blood retinal barrier in young diabetic patients. Diabetes 27:85–87
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Supported by grants from the Research Fund of Aalborg City Council, the Northern Jutland Medical Research Fund, P. Carl Petersen Fund, and the Danish Medical Research Council
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Kjaergaard, JJ. Fluorophotometric studies of twenty-nine healthy subjects. Graefe's Arch Clin Exp Ophthalmol 222, 267–268 (1985). https://doi.org/10.1007/BF02133696
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DOI: https://doi.org/10.1007/BF02133696