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Feeding tests with ducklings, Turkey chicks and rabbits and the effects of aflatoxin on these animals

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Abstract

The effects of feeding animals with a toxic strain ofA. flavus was examined. The animals examined were ducklings, turkeys and rabbits. All of them showed loss of weight and mortality after feeding with aflatoxin.

The livers of those animals showed that aflatoxin caused pathological changes. This damage of the liver is the lethal effect of the aflatoxin.

Zusammenfassung

Die Wirkung der Fütterung von Tieren mit einem toxischen Stamm vonA. flavus wurde untersucht. Die Tiere sind Entchen, Truthähnchen und Hasen. Alle zeigten einen Gewichtverlust und eine Mortalität nach Aflatoxin-Fütterung. Die Leber der Tiere zeigte, daß Aflatoxin pathologische Veränderung herbeiführte. Die Leberschädigung ist die tötliche Wirkung des Aflatoxins.

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References

  • Allcroft, R. (1965). Aspects of aflatoxicosis in farm animals. In:G. N. Wogan (ed.) “Mycotoxins in foodstuffs” M.I.T. Press, Cambridge, Mass. p. 153–162.

    Google Scholar 

  • Armbrecht, B. H., Hodges, F. A., Smith, H. R. &Nelson, A. A. (1963). Mycotoxins. I. Studies on aflatoxin derived from contaminated peanut meal and certain strains ofAspergillus flavus.J. Assoc. Offic. Agr. Chemists 46:805–817.

    Google Scholar 

  • Armbrecht, B. H. &Fitzhugh, O. G. (1964). Mycotoxins. II. The biological assay of aflatoxin in Peking white ducklings.Toxicol. Appl. Pharmacol., 6:421–426.

    Google Scholar 

  • Armbrecht, B. H., Bierbower, G. W. &Underwood, P. C. (1965). Experimental Aflatoxicosis in Peking White Ducklings and Coturnix Quail.Toxicol. appl. Pharmacol. 7:478.

    Google Scholar 

  • Ashley, L. M., Halver, J. E., Gardner, W. K. &Wogan, G. N. (1965). Crystalline aflatoxins cause trout hepatoma.Fed. Proc. Part I, 24:627.

    Google Scholar 

  • Asplin, F. D. &Carnaghan, R. B. A. (1961). The toxicology of certain groundnut meals for poultry with special reference to their effect on ducklings and chickens.Vet. Rec. 73, 46:1215–1219.

    Google Scholar 

  • Barnes, J. M. (1967). Toxic fungi with special reference to aflatoxin.Trop. Sci. IX, 2:64–74.

    Google Scholar 

  • Barnes, J. M. &Butler, W. H. (1964). Carcinogenic activity of aflatoxin to rats.Nature, 202:1016.

    Google Scholar 

  • Blount, W. P. (1961). Turkey “X” disease.J. Brit. Turkey Fed., 9:52.

    Google Scholar 

  • Borut, S. &Joffe, A. Z. (1966).Aspergillus flavus Link, aflatoxins and toxicity of groundnuts in Israel.Israel J. Bot., 14:198.

    Google Scholar 

  • Butler, W. H. &Barnes, J. M. (1966). Carcinoma of the glandular stomach in rats given diets containing aflatoxin.Nature, 209:90.

    Google Scholar 

  • Carnaghan, R. B. A., Hartley, R. D. &O'Kelly, J. (1963). Toxicity and fluorescence properties of the aflatoxins.Nature, 200:1101.

    Google Scholar 

  • Diener, U. L., Davis, N. D., Salmon, W. D. &Prickett, C. O. (1963). Toxin producingAspergillus isolated from domestic peanuts.Science, 142:1491–1492.

    PubMed  Google Scholar 

  • Goldblatt, L. A. (1965). Aflatoxin.Assoc. Food Drug Offic. U.S., 29, 4:158–169.

    Google Scholar 

  • Harding, J. D. J., Done, J. T., Lewis, G., &R. Allcroft (1963). Experimental groundnut poisoning in pigs.Res. Vet. Sci.,4, 2:217–229.

    Google Scholar 

  • Hintz, H. F., Booth, A. N., Cucullu, A. F., Gardner, H. K. &Heitman, H. (1967). Aflatoxin toxicity in swine.Proc. Soc. Exp. Biol. Med. 124:266–268.

    PubMed  Google Scholar 

  • Lancaster, M. C., Jenkins, F. P. &Philip, J. Mel. (1961). Toxicity associated with certain samples of groundnuts.Nature, 192,4807:1095–1096.

    Google Scholar 

  • Legator, M. S., &Withrow, A. J. (1964). Aflatoxin: effect on mitotic division in cultured embryonic lung cells.J. Assoc. Offic. Agr. Chem. 47, 6:1007–1009.

    Google Scholar 

  • Loosmore, R. M. &Harding, J. D. J. (1961). A toxic factor in Brazilian groundnut causing liver damage in pigs.Vet. Rec. 73, 49:1362–1364.

    Google Scholar 

  • Newberne, P. M., Wogan, G. N., Carlton, W. W. &Abdel-Kader, M. M. (1964). Histopathologic lesions in ducklings caused byAspergillus flavus cultures, culture extracts, and crystalline aflatoxins.Toxicol. Appl. Pharmacol. 6:542–556.

    Google Scholar 

  • Newberne, P. M. (1965). Carcinogenicity of aflatoxin-contaminated peanut meal. In:G. N. Wogan (ed.) Mycotoxins in Foodstuffs. M.I.T. Press, Cambridge Mass. p. 187–208.

    Google Scholar 

  • Newberne, P. M., Russo, R. &Wogan, G. N. (1966). Acute toxicity of aflatoxin B1 in the dog.Pathol. Vet. 3:331–340.

    PubMed  Google Scholar 

  • Peers, F. G. (1967). Aflatoxin — A summary of recent work.Trop. Sci. IX, 4:186–203.

    Google Scholar 

  • Pons, W. A. Jr., Cucullu, A. F., Lee, L. S., Robertson, J. A., Franz, A. O. &Goldblatt, L. A. (1966). Determination of aflatoxins in agricultural products — use of aqueous acetone for extraction.J. Assoc. Offic. Agr. Chem. 49, 3:554–562.

    Google Scholar 

  • Report of the International working party on groundnut toxicity research. (1962). Toxicity associated with certain batches of groundnut. 16 pp.

  • Roegner, F. R. (1967). The FDA looks at aflatoxins. 38th Annual Technical Conference of the Grain Elevator and Processing Superintendents Association, Chicago, Ill. February 28. 10 pp.

  • Tulpule, P. G., Madhaven, T. V. &Gopalan, C. (1964). Effect of feeding aflatoxin to young monkeys.Lancet 1:962–963.

    Google Scholar 

  • Verrett, M. J., J. P. Marliac &McLaughlin, J. Jr. (1964). Use of the chicken embryo in the assay of aflatoxin toxicity.J. Assoc. Offic. Agr. Chem. 47, 6:1003–1006.

    Google Scholar 

  • Wilson, B. J. &Wilson, C. H. (1964). Toxin fromAspergillus flavus: Production on food materials of a substance causing tremors in mice.Science 144, 3615:177–178.

    PubMed  Google Scholar 

  • Wogan, G. N. (1965). Experimental toxicity and carcinogenicity of aflatoxins. In:G. N. Wogan (ed.) Mycotoxins in Foodstuffs. M.I.T. Press Cambridge, Mass. p. 163–173.

    Google Scholar 

  • Wogan, G. N. (1966). Chemical nature and biological effects of the aflatoxins.Bacterial Rev. 30:460–470.

    Google Scholar 

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Research supported by grant number FG-Is-161 of the United States Department of Agriculture to whom the author is indebted.

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Joffe, A.Z. Feeding tests with ducklings, Turkey chicks and rabbits and the effects of aflatoxin on these animals. Mycopathologia et Mycologia Applicata 40, 49–61 (1970). https://doi.org/10.1007/BF02128661

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