Agents and Actions

, Volume 26, Issue 1–2, pp 165–166 | Cite as

Prostaglandin E2 and leukotriene C4 modulate interleukin-1 inhibition of WEHI-3B tumor cell growthin vitro

  • G. R. Elliott
  • C. Tak
  • I. L. Bonta
Cytokines and Macrophage Activation


Tumor Cell Prostaglandin 


  1. [1]
    C. A. Dinarello,The biology of interleukin-1 and comparison to tumor necrosis factor. Immunology Letters.16, 227–232 (1987).PubMedGoogle Scholar
  2. [2]
    S. L. Kunkel, S. W. Chensue and S. H. Phan,Prostaglandins as endegenous mediators of interleukin 1 production. J. Immunol.136, 186–192 (1986).PubMedGoogle Scholar
  3. [3]
    M. Rola-Pleszczynski and J. Lemaire,Leukotrienes augment interleukin-1 production by human monocytes. J. Immunol.135, 3958–3961.Google Scholar
  4. [4]
    I. L. Bonta and M. J. Parnham,Immunomodulatory-antiinflammatory functions of E-type prostaglandins. Minireview with emphasis on macrophage mediated effects. Int. J. Immunopharmac.4, 103–109 (1982).Google Scholar
  5. [5]
    D. Metcalf and N. A. Nicola,Autoinduction of differentiation in WEHI-3B leukemia cells. Int. J. Cancer.30, 773–780 (1982).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1989

Authors and Affiliations

  • G. R. Elliott
    • 1
  • C. Tak
    • 1
  • I. L. Bonta
    • 1
  1. 1.Department of PharmacologyErasmus University RotterdamRotterdamThe Netherlands

Personalised recommendations