Cardiovascular Drugs and Therapy

, Volume 1, Issue 1, pp 51–55 | Cite as

Converting enzyme inhibitors (captopril, enalapril, perindopril) prevent early-post infarction ventricular fibrillation in the anaesthetized rat

  • C. Ribuot
  • L. Rochette
Focussed Section: ACE Inhibitors


The angiotensin-converting enzyme inhibitors, captopril, enalapril and perindopril, exert antiarrhythmic effects on early post-infarction arrhythmias in anaesthetized rats. These studies support the hypothesis that converting enzyme inhibitors could have a “cardioprotective” effect, but the doses used are probably “high” in relation to those therapeutically applicable to man.

Key words

converting enzyme inhibitors antiarrhythmic effects 


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Copyright information

© Martinus Nijhoff Publishing 1987

Authors and Affiliations

  • C. Ribuot
    • 1
  • L. Rochette
  1. 1.Laboratoire de Pharmacodynamie et de Physiologie PharmaceutiqueFaculté de Pharmacie-Université de DIJON-7 Bd. J.d'Arc 21000DijonFrance

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