Abstract
A chlorhexidine-lidocaine jelly (Instillagel, Farco-Pharma, Giessen, GFR) was tested for antibacterial properties. In 50 patients with diverse urological diseases urethral swabs were taken prior to and after 10-min exposure to the jelly, and the specimens were cultured in liquid and blood agar media. Forty-six of the 50 swabs contained pathogenic bacteria prior to application of the jelly, whereas after 10-min exposure only 17 and 12 swabs yielded pathogenic bacteria in the liquid and agar media, respectively, the number of colonies being also significantly reduced. It is concluded that Instillagel might be of value in reducing the frequency of urinary tract infections after instrumental procedures.
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References
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Tabacov, I., Tsatsova, V. The antibacterial effect of a chlorhexidine-lidocaine Jelly upon the flora of the anterior male urethra. International Urology and Nephrology 2, 199–202 (1970). https://doi.org/10.1007/BF02125821
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DOI: https://doi.org/10.1007/BF02125821