Summary
The kinetic parameters of D2O intake in the frog sciatic nerve are obtained by means of infrared spectroscopy. 3 aqueous compartments: a non-exchangeable one (≈29%) and 2 compartments of quasi-free exchangeable water: ≈50% intracellular and ≈21% extracellular, are revealed.
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The first communication in this series is V. Vasilescu, D.-G. Mārgineanu and Eva Katona, Naturwiss.62, 187 (1975).
For such derivations reference is made to the above mentioned mathematical model or to related works on compartmental analysis, reviewed by A. Rescigno and J. S. Beck, in: Foundations of Mathematical Biology, vol. II. Ed. R. Rosen, Academic Press, New York 1972.
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Vasilescu, V., Margineanu, D.G. & Katona, E. Heavy water intake in tissues. II. H2O−D2O exchange in the myelinated nerve of the frog. Experientia 33, 192–194 (1977). https://doi.org/10.1007/BF02124060
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DOI: https://doi.org/10.1007/BF02124060