Skip to main content
Log in

Heavy water intake in tissues. II. H2O−D2O exchange in the myelinated nerve of the frog

  • Published:
Experientia Aims and scope Submit manuscript

Summary

The kinetic parameters of D2O intake in the frog sciatic nerve are obtained by means of infrared spectroscopy. 3 aqueous compartments: a non-exchangeable one (≈29%) and 2 compartments of quasi-free exchangeable water: ≈50% intracellular and ≈21% extracellular, are revealed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. J. J. Katz and R. L. Crespi, in: Isotope Effects in Chemical Reactions. Ed. C. J. Collins and N. S. Bowman. Van Nostrand, New York 1971.

    Google Scholar 

  2. S. Lewin, Displacement of Water and its Control of Biochemical Reactions, ch. 8. Academic Press, London 1974.

    Google Scholar 

  3. L. Bass and W. J. Moore, Prog. Biophys. mol. Biol.27, 145 (1973).

    Article  Google Scholar 

  4. A. F. Brading and A. W. Jones, J. Physiol.200, 387 (1969).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. B. C. Elford, J. Physiol.211, 73 (1970).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. V. Vasilescu, Eva Katona and D.-G. Mārgineanu, Studia Biophys52, 223 (1975).

    CAS  Google Scholar 

  7. D.-G. Mārgineanu, J. theor. Biol.61 377 (1976).

    Article  PubMed  Google Scholar 

  8. P. S. Belton, R. R. Jackson and K. J. Packer, Biochim. Biophys. Acta286, 16 (1972).

    Article  CAS  PubMed  Google Scholar 

  9. M. M. Civan and M. Shporer, Biophys. J15, 299 (1975).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

The first communication in this series is V. Vasilescu, D.-G. Mārgineanu and Eva Katona, Naturwiss.62, 187 (1975).

For such derivations reference is made to the above mentioned mathematical model or to related works on compartmental analysis, reviewed by A. Rescigno and J. S. Beck, in: Foundations of Mathematical Biology, vol. II. Ed. R. Rosen, Academic Press, New York 1972.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vasilescu, V., Margineanu, D.G. & Katona, E. Heavy water intake in tissues. II. H2O−D2O exchange in the myelinated nerve of the frog. Experientia 33, 192–194 (1977). https://doi.org/10.1007/BF02124060

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02124060

Keywords

Navigation