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Release of Fc-receptors after streptococcal lysis induced by a lytic enzyme fromStreptomyces globisporus

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Abstract

Streptomyces globisporus produced an enzyme which had lytic effects on streptococci and was able to solubilize their Fc-receptors. A new method for rapid purification of this enzyme was described. It consisted of adsorption to Amberlite CG 50 and subsequent chromatography on CM-cellulose Whatman CM 52. The purified enzyme was free of proteases and had lysed streptococci of serological groups A, B, C, G and L. It released Fcreceptors from the streptococcal surface in a biologically active form.

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Authors and Affiliations

  1. Institut für Bakteriologie und Immunologie, Fachbereich Veterinärmedizin, Justus-Liebig-Universität Giessen, Frankfurter Strasse 107, D-6300, Giessen, Federal Republic of Germany

    D. Tille, G. S. Chhatwal & H. Blobel

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  1. D. Tille
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  2. G. S. Chhatwal
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  3. H. Blobel
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Tille, D., Chhatwal, G.S. & Blobel, H. Release of Fc-receptors after streptococcal lysis induced by a lytic enzyme fromStreptomyces globisporus . Med Microbiol Immunol 175, 35–41 (1986). https://doi.org/10.1007/BF02123127

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  • DOI: https://doi.org/10.1007/BF02123127

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