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Medical Microbiology and Immunology

, Volume 161, Issue 4, pp 253–261 | Cite as

Antigenic relationship between the surface antigens of avian and Equine influenza viruses

  • R. Rott
  • H. Becht
  • M. Orlich
Article

Abstract

Influenza virus Equine 1 (A/equine/Prague/56) has a hemagglutinin which is antigenically related to the hemagglutinin of fowl plague virus strain Rostock (FPV) and a neuraminidase which cross-reacts with the enzyme of virus N (A/chick/Germany/49). After a single injection of chickens with Equine 1 virus no hemagglutination inhibiting (HI) and neutralizing antibodies against FPV can be demonstrated, although the birds are fully protected against a lethal dose of FPV. HI and neutralizing antibodies against FPV appear after a second injection of Equine 1 virus several weeks after the first one. Liberation of newly synthesized FPV from the host cell is inhibited by antibodies cross-reacting with any antigen of the virus surface.

Keywords

Influenza Host Cell Influenza Virus Surface Antigen Virus Strain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • R. Rott
    • 1
  • H. Becht
    • 1
  • M. Orlich
    • 1
  1. 1.Institut für VirologieJustus Liebig-UniversitätGießen

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