Medical Microbiology and Immunology

, Volume 161, Issue 4, pp 253–261 | Cite as

Antigenic relationship between the surface antigens of avian and Equine influenza viruses

  • R. Rott
  • H. Becht
  • M. Orlich


Influenza virus Equine 1 (A/equine/Prague/56) has a hemagglutinin which is antigenically related to the hemagglutinin of fowl plague virus strain Rostock (FPV) and a neuraminidase which cross-reacts with the enzyme of virus N (A/chick/Germany/49). After a single injection of chickens with Equine 1 virus no hemagglutination inhibiting (HI) and neutralizing antibodies against FPV can be demonstrated, although the birds are fully protected against a lethal dose of FPV. HI and neutralizing antibodies against FPV appear after a second injection of Equine 1 virus several weeks after the first one. Liberation of newly synthesized FPV from the host cell is inhibited by antibodies cross-reacting with any antigen of the virus surface.


Influenza Host Cell Influenza Virus Surface Antigen Virus Strain 
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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • R. Rott
    • 1
  • H. Becht
    • 1
  • M. Orlich
    • 1
  1. 1.Institut für VirologieJustus Liebig-UniversitätGießen

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