Medical Microbiology and Immunology

, Volume 160, Issue 2–3, pp 210–210 | Cite as

Immunosuppression by measles virus

  • C. J. Lucas
Part Two Pathogenetic Aspects


In 1908 Von Pirquet noted that during a measles virus infection, but before the onset of the rash, former positive skintests (PPD) were negative. Since then this has in vivo been confirmed by many investigators. More recent experiments on the in vivo effects of measles virus on lymphocyte activities have yielded conflicting results. It will be shown that it might be essential to use purified measles virus to obtain interpretable data.

Results obtained by infecting lymphocytes with purified measles virus on their subsequent stimulation by mitogen or antigen will be given.


Virus Infection Measle Recent Experiment Measle Virus Lymphocyte Activity 
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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • C. J. Lucas
    • 1
  1. 1.Central Laboratory of the Netherlands Red CrossBlood Transfusion ServiceAmsterdam

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