Skip to main content
SpringerLink
Log in

The immune response of (C57BL/6 X C3H)F1 mice to the endogenous AKR-MuLV

  • Published:
Medical Microbiology and Immunology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bassin, R.H., Tuttle, N., Fischinger, P.J.: Rapid cell culture assay technique for murine leukemia viruses. Nature229, 564–566 (1971)

    Google Scholar 

  2. Fischinger, P.J., Ihle, J.N., Bolognesi, D.P., Schäfer, W.: Inactivation of murine xenotropic oncornavirus by normal mouse sera is not immunoglobulin-mediated. Virology71, 346–351 (1976)

    PubMed  Google Scholar 

  3. Fischinger, P.J., Schäfer, W., Bolognesi, D.P.: Neutralization of homologous and heterologous oncornaviruses by antisera against p15(E) and gp71 polypeptides of Friend murine leukemia virus. Virology71, 169–184 (1976)

    PubMed  Google Scholar 

  4. Ihle, J.N., Denny, T., Bolognesi, D.: Purification and serological characterization of the major envelope glycoprotein from AKR murine leukemia virus and its reactivity with autogenous immune sera from mice. J. Virol.17, 727–736 (1976)

    PubMed  Google Scholar 

  5. Ihle, J.N., Domotor, J.J., Jr., Bengali, K.M.: Strain-dependent development of an autogenous immune response in mice to endogenous C-type viruses, pp. 177–179. In: Bibliotheca Haematologica, ed. by J. Clemmesen and D.S. Yohn. Basel, Switzerland: Karger AG 1976

    Google Scholar 

  6. Ihle, J.N., Domotor, J.J., Jr., Bengali, K.: Characterization of the type and group specificities of the immune response in mice to murine leukemia viruses. J. Virol.18, 124–131 (1976)

    PubMed  Google Scholar 

  7. Ihle, J.N., Hanna, M.G., Jr., Roberson, L.E., Kenney, F.T.: Autogenous immunity to endogenous RNA tumor virus: Identification of antibody reactivity to select viral antigens. J. Exp. Med.139, 1568–1581 (1974)

    PubMed  Google Scholar 

  8. Ihle, J.N., Hanna, M.G., Jr., Schäfer, W., Hunsmann, G., Bolognesi, D.P., Hüper, G.: Polypeptides of mammalian oncornaviruses. III. Localization and reactivity of p15 with natural antibody. Virology63, 60–67 (1975)

    PubMed  Google Scholar 

  9. Ihle, J.N., Joseph, D.R., Pazmino, N.H.: Radiation leukemia in C57B1/6 mice. II. Lack of overt ecotropic virus expression in the majority of lymphomas. J. Exp. Med.144, 1406–1423 (1976)

    PubMed  Google Scholar 

  10. Ihle, J.N., Lazar, B.: Natural immunity in mice to the envelope glycoprotein of endogenous ecotropic type C viruses: Neutralization of virus infectivity. J. Virol.21, 974–980 (1977)

    PubMed  Google Scholar 

  11. Ihle, J.N., McEwan, R., Bengali, K.: Radiation leukemia in C57BL/6 mice. I. Lack of serological evidence for the role of endogenous ecotropic viruses in pathogenesis. J. Exp. Med.144, 1391–1405 (1976)

    PubMed  Google Scholar 

  12. Ihle, J.N., Yurconic, M., Jr., Hanna, M.G., Jr.: Autogenous immunity to endogenous RNA tumor virus. Radioimmune precipitation assay of mouse serum antibody levels. J. Exp. Med.138, 194–208 (1973)

    PubMed  Google Scholar 

  13. Lee, J.C., Ihle, J.N.: Characterization of the blastogenic and cytotoxic response of normal mice to ecotropic C type viral gp71. J. Immunol.118, 928–93 (1977)

    PubMed  Google Scholar 

  14. Lowy, D.R., Chattopadhyay, S.K., Teich, N.M., Rowe, W.P., Levine, A.S.: AKR murine leukemia virus genome: Frequency of sequences in DNA of high-, low-, and non-virus-yielding mouse strains. Proc. Natl. Acad. Sci. USA71, 3555–3559 (1974)

    PubMed  Google Scholar 

  15. Rowe, W.P.: Genetic factors in the natural history of murine leukemia virus infection: G.H.A. Clowes Memorial Lecture, Cancer Res.33, 3061–3068 (1973)

    PubMed  Google Scholar 

  16. Schäfer, W., Hunsmann, G., Moennig, V., de Noronha, F., Bolognesi, D.P., Green, R.W., Hüper, G.: Polypeptides of mammalian oncornaviruses. II. Characterization of a murine leukemia virus polypeptide (p15) bearing interspecies reactivity. Virology63, 48–59 (1975)

    PubMed  Google Scholar 

  17. Steeves, R.A., Strand, M., August, J.T.: Structural proteins of mammalian oncogenic RNA viruses: Murine leukemia virus neutralization by antisera prepared against purified envelope glycoprotein. J. Virol.14, 187–189 (1975)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Basic Research Program, NCI Frederick Cancer Research Center, 21701, Frederick, Maryland, USA

    James N. Ihle & John C. Lee

Authors
  1. James N. Ihle
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. John C. Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Dedicated to Professor Werner Schäfer on the occasion of his 65th birthday

Research sponsored by the National Cancer Institute under Contract No. N01-CO-25423 with Litton Bionetics, Inc.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ihle, J.N., Lee, J.C. The immune response of (C57BL/6 X C3H)F1 mice to the endogenous AKR-MuLV. Med Microbiol Immunol 164, 207–216 (1977). https://doi.org/10.1007/BF02121315

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02121315

Keywords

Search

Navigation