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Medical Microbiology and Immunology

, Volume 166, Issue 1–4, pp 133–139 | Cite as

Growth of some attenuated influenza A viruses in hamsters

  • P. Reeve
Article

Abstract

The replication of three attenuated influenza viruses in SPF hamsters inoculated by aerosol was investigated. Strains A2-Eng, A2-Victoria, ts-1-[E] A2-Victoria recombinant, and the RIT 4050 strain all multiplied to high liters in hamster lungs and induced both primary and secondary serological responses. Recombinant strain, A/AA/6/60-A2-Vic (CR22) multiplied to lower titers in hamsters. Differences were observed between the infectivity of different strains for hamsters, the wild-type viruses A2-Eng and A2-Vic being the most infective.

Keywords

Influenza Influenza Virus Recombinant Strain Lower Titer Serological Response 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • P. Reeve
    • 1
  1. 1.Sandoz ForschungsinstitutWienAustria

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