Medical Microbiology and Immunology

, Volume 161, Issue 3, pp 211–213 | Cite as

Some particularities of hepatitis B-antigen subdeterminants

  • A. Cruceanu
  • V. T. BabeŞ
  • R. Lenkei
  • S. Cepanaru
  • G. Kloos


From 200 acute viral hepatitis patients serum samples were collected successively, at various intervals. In 192 patients one single hepatitis B-antigen (HB-Ag) subdeterminant (“ad” in 37.6% and “ay” in 62.4% of the cases) occurred and persisted during the entire course of the disease. The remained 8 patients (4%) showed an alternation of HB-Ag subdeterminants. The possible causes of this alternation are discussed in detail.


Hepatitis Serum Sample Viral Hepatitis Patient Serum Acute Viral Hepatitis 
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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • A. Cruceanu
    • 1
    • 4
  • V. T. BabeŞ
    • 1
  • R. Lenkei
    • 2
  • S. Cepanaru
    • 3
  • G. Kloos
    • 3
  1. 1.“Stefan S. Nicolau” Institute of VirologyBucharest
  2. 2.“Dr. V. BabeŞ” Institute of Pathology and Medical GeneticsBucharest
  3. 3.Hospital of Communicable DiseasesBraŞov
  4. 4.Bucharest Str. M. CaldruŞani Ni 9, Sect.8The National Institute of Gerontology and GeriatricsBucharestRumania

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