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The m protein of influenza viruses has no immunizing effect

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Abstract

Influenza A virus M protein was prepared by electrophoresis in SDS polyacrylamide gel from virus particles which had been pretreated with octylglucoside to remove the surface glycoproteins. M antigens from the influenza virus strains A/Victoria/3/75 (H3N2), A/FPV/Rostock (Hav1N1) and A/chick/ Germany/49 (Hav2Neq1) did not protect mice against a lethal challenge infection with the virulent Victoria strain.

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Authors and Affiliations

  1. Institut für Virologie, Justus-Liebig-UniversitÄt Giessen, Germany

    H. Becht & R. Rott

  2. Behringwerke AG, Marburg, Germany

    H. Gruschkau

Authors
  1. H. Becht
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  2. H. Gruschkau
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  3. R. Rott
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Supported by the Deutsche Forschungsgemeinschaft (Sonderforschungsbereich 47)

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Becht, H., Gruschkau, H. & Rott, R. The m protein of influenza viruses has no immunizing effect. Med Microbiol Immunol 167, 285–288 (1979). https://doi.org/10.1007/BF02120814

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  • DOI: https://doi.org/10.1007/BF02120814

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