Skip to main content
SpringerLink
Log in

Untersuchungen über den Einfluß des Kationenmilieus und verschiedener Pharmaka auf die Kontraktilität und Autorhythmik eines spontan aktiven glatten Gefäßmuskels in vitro

  • Published:
Archiv für Kreislaufforschung Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  • Abboud, F. M., J. W. Eckstein, B. G. Zimmermann andM. H. Graham, Sensitization of arteries, veins, and small vessels to norepinephrine after cocain. Circ. Res.15, 247 (1964).

    PubMed  Google Scholar 

  • Altura, B. M., S. G. Hershey andB. W. Zweifach, Effects of a synthetic analogue of vasopressin on vascular smooth muscle. Proc. Soc. exp. Biol. Med.119, 258 (1965).

    PubMed  Google Scholar 

  • Ariens, E. J., Wirkung und Wirkungsmechanismus von Katecholaminen und ihren Derivaten. Naunyn-Schmiedebergs Arch. Pharmak. exp. Path.257, 118 (1967).

    Google Scholar 

  • Axelsson, J., B. Johannsson, O. Jonsson andB. Wahlstrom, The effects of adrenergic drugs on electrical and mechanical activity of the portal vein. In: Symposium on Electrical Activity and Innervation of Blood Vessels, S. 16, (Basel 1967).

  • Axelsson, J., N. Wahlström, B. Johansson andO. Jonsson, Influence of the ionic environment on spontaneous electrical and mechanical activity of the rat portal vein. Circulat Res.21, 609 (1967).

    PubMed  Google Scholar 

  • Barr, L., V. E. Headings andD. F. Bohr, Potassium and the recovery of arterial smooth muscle after cold storage. J. gen. Physiol.46, 19 (1962).

    PubMed  Google Scholar 

  • Barr, L. andR. L. Malvin, Estimation of extracellular spaces of smooth muscle using different-sized molecules. Amer. Physiol.208, 1042 (1965).

    Google Scholar 

  • Bassenge, E., P. Walter undU. Doutheil, Wirkungsumkehr der adrenergischen Coronargefäßreaktion in Abhängigkeit vom Coronargefäßtonus. Pflügers Arch. ges. Physiol.297, 146 (1967).

    Google Scholar 

  • Berde, B., W. Schalch undW. Doepfner, Über die lokalvasoconstrictorische Wirkung von Octapressin, Adrenalin und Hypertensin. Helv. Physiol. Pharmacol. Acta22, 110 (1964).

    PubMed  Google Scholar 

  • Berde, B., Some observations on the circulatory effects of oxytocin, vasopressin and similar polypeptides. In: Advances in Oxytocin S. 11 (Oxford 1965).

  • Bohr, D. F., D. C. Brodie andD. H. Cheu, Effect of electrolytes on arterial muscle concentration. Circulation17, 746 (1958).

    PubMed  Google Scholar 

  • Bohr, D. F. andP. L. Goulet, Role of electrolytes in the contractile machinery of vascular smooth muscle. Amer. J. Cardiol.8, 549 (1961).

    Google Scholar 

  • Bohr, D. F., P. L. Goulet andA. C. Taquini, Direct tension recording from smooth muscle of resistance vessels from various organs. Angiology12, 478 (1961).

    PubMed  Google Scholar 

  • Bohr, D. F., Contraction of vascular smooth muscle. Canad. med. Ass. J.90, 174 (1964).

    PubMed  Google Scholar 

  • Bohr, D. F., Electrolytes and smooth muscle contration. Pharmacol. rev.16, 85 (1964).

    PubMed  Google Scholar 

  • Booz, K.-H., Experimentelle und morphologische Beobachtungen an der Vena portae der weißen Ratte. Ann. Univ. Sarav. Med.7, 115 (1959).

    PubMed  Google Scholar 

  • Bozler, E., Contraclility of muscle in solutions of low electrolyte concentration. Amer. J. Physiol.199, 299 (1960).

    Google Scholar 

  • Bozler, E., Initiation of contraction in smooth muscle. Physiol. Rev.42, suppl. 5, 179, (1962).

    Google Scholar 

  • Brecht, K., J. A. Estada undA. Götz, Zur Beeinflussung der Gefäßmotorik durch Ca++- und K+-Ionen. Pflügers Arch. ges. Physiol.279, 330 (1964).

    Google Scholar 

  • Briggs, A. H. andS. Melvin, Ion movements in isolated rabbit aortic strips. Amer. Physiol.201, 365 (1961).

    Google Scholar 

  • Bueding, E. andE. Bülbring, The inhibitory action of adrenaline. Biochemical and biophysical observations. In: Pharmacology of Smooth Muscle. IInd Int. Pharmac. Meeting,6, 37 (1964).

  • Bülbring, E., H. Kuriyama andB. Twarog, Influence of sodium and calcium on spontaneous spike generation in smooth muscle. J. Physiol.161, 48 P (1962).

    Google Scholar 

  • Bülbring, E. andH. Kuriyama, Effects of changes in the external sodium and calcium concentrations on spontaneous electrical activity in smooth muscle of guinea pig taenia coli. J. Physiol.166, 29 (1963).

    PubMed  Google Scholar 

  • Bülbring, E. undK. Golenhofen, Fortlaufende Messung von Sauerstoffverbrauch, elektrischer Aktivität und mechanischer Spannung an spontan aktiver glatter Muskulatur. Pflügers Arch. ges. Physiol.283, R 39 (1965).

    Google Scholar 

  • Burks, T. F., andT. Cooper, Enhancement of peripheral alpha-receptors, stimulation by blockade of “silent” beta receptors. Circulat. Res.21, 703 (1967).

    PubMed  Google Scholar 

  • Carrier, O. jr., J. R. Walker andA. C. Guyton, Role of oxygen in autoregulation of blood flow in isolated vessels. Amer. J. Physiol.206, 951 (1964).

    PubMed  Google Scholar 

  • Cuthbert, A. W. andM. C. Sutter, Electrical activity of a mammalian vein. Nature202, 95 (1964).

    Google Scholar 

  • Cuthbert, A. W. andM. C. Sutter, The effects of drugs on the relation between the action potential discharge and tension in a mammalian vein. Brit. J. Pharmac.25, 592 (1965).

    Google Scholar 

  • Davignon, U., R. R. Lorenz andJ. T. Silepherd, Response of human umbilical artery to changes in transmural pressure. Amer. Physiol.209, 51 (1965).

    Google Scholar 

  • Dodd, W. A. andE. E. Doniel, Vascular muscle reactivity. Circulat. Res.8, 446 (1960).

    Google Scholar 

  • Eichna, L. W., Proceedings of a Symposium on Vascular Smooth Muscle. Physiol. Rev.42, Suppl. 5 (1962).

  • Folkow, B., B. Johansson andS. Mellander, The comparative effects of angiotensin and noradrenaline on consecutive vascular segments. Acta physiol. scand.,53, 99 (1961).

    PubMed  Google Scholar 

  • Funaki, S. andD. F. Bohr, Electrical and mechanical activity of isolated vascular smooth muscle of the rat. Nature203, 192 (1964).

    Google Scholar 

  • Furchgott, R. F., The pharmacology of vascular smooth muscle. Pharmacol. Rev., 7, 183 (1955).

    PubMed  Google Scholar 

  • Golenhofen, K., Elektrophysiologische Untersuchungen zur Minutenrhythmik der glatten Muskulatur (Taenia coli des Meerschweinchens). Naunyn-Schmiedebergs Arch. Pharmakol. exp. Path.257, 277 (1967).

    Google Scholar 

  • Hagemeijer, F., G. Rorive andE. Schoffeniels, The ionic composition of rat aortic muscle fibers. Arch. int. Physiol.73, 453 (1965).

    PubMed  Google Scholar 

  • Hanenson, I. B., Effect of electrolytes and hormones on contraction of arterial smooth muscle. Circulation26, 727 (1962).

    Google Scholar 

  • Hinke, J. A. M. undM. L. Wilson, Effects of electrolytes on contractility of artery segments in vitro. Amer. Physiol.203, 1161 (1962).

    Google Scholar 

  • Hinke, J. A. M., M. L. Wilson andS. C. Burnham, Calcium and the contractility of arterial smooth muscle. Amer. J. Physiol.206, 211 (1964).

    PubMed  Google Scholar 

  • Hughes, J. andJ. R. Vane, An analysis of drug responses of the rabbit portal vein to drugs and electrical stimulation. Brit. J. Pharmacol.30, 46 (1967).

    Google Scholar 

  • Hughes, J., Potention by veratrine of the responses of isolated vascular tissue to tyramine and sympathetic nerve stimulation. Naunyn-Schmiedebergs Arch. Pharmakol. exp. Path.259, 177 (1968).

    Google Scholar 

  • Johansson, B. andD. F. Bohr, Rhythmic activity in smooth muscle of small subcutaneous arteries. Amer. Physiol.210, 801 (1966).

    Google Scholar 

  • Johansson, B., O. Johnsson, J. Axelsson andB. Wahlström, Electrical and mechanical characteristics of vascular smooth muscle response to norepinephrine and isoproterenol. Circulat. Res.21, 619 (1967).

    PubMed  Google Scholar 

  • Johansson, B. andB. L. Ljung, Spread of excitation in the smooth muscle of the rat portal vein. Acta physiol. Scand.70, 312 (1967).

    PubMed  Google Scholar 

  • Johansson, B. andO. Johnsson, Cell volume as a factor influencing electrical and mechanical activity of vascular muscle. Acta Physiol. Scand.72, 456 (1968).

    PubMed  Google Scholar 

  • Keatinge, W. R., Mechanism of adrenergic stimulation of mammalian arteries and its failure et low temperatures. J. Physiol.174, 184 (1964).

    PubMed  Google Scholar 

  • Keatinge, W. R., Sympathomimetic action of acetylcholine on cell membrane potential of blood vessels. J. Physiol.181, 75 P (1965).

    Google Scholar 

  • Keatinge, W. R., Ionic requirements for arterial action potential. J. Physiol.194, 169 (1968).

    PubMed  Google Scholar 

  • Keatinge, W. R., Sodium flux and electrical activity of arterial smooth muscle. J. Physiol.194, 183 (1968).

    PubMed  Google Scholar 

  • Kohlhardt, M., D. Voth, K. Wirth undJ. Dudek, Über den Einfluß von Calcium2+ und Hypothermie auf den mechanischen Systolenbeginn des isolierten Katzenherzens. Arch. Kreislaufforschg.54, 43 (1967).

    Google Scholar 

  • Kohlhardt, M., D. Voth, K. Wirth undJ. Dudek, Zur Frage des asynchronen mechanischen Systolenbeginns beider Ventrikel am isolierten Herzen. Z. ges. exp. Med.144, 120 (1967).

    Google Scholar 

  • Leonard, E., Alteration of contractile response of artery strips by a potassium-free solution, cardiac glycosides and changes in stimulation frequency. Amer. J. Physiol.189, 185 (1957).

    PubMed  Google Scholar 

  • Lüttgau, H. C. andR. Niedergerke, The antagonism between Ca and Na ions on the frog's heart. J. Physiol.143, 486 (1958).

    PubMed  Google Scholar 

  • Lundholm, L. andE. Mohme-Lundholm, Length at inactivated contractile elements, length-tension diagram, active status and tone of vascular smooth muscle. Acta physiol. Scand.68, 347 (1966).

    Google Scholar 

  • Mallov, S., Effects of sodium ion and solution tonicity on reactivities of hypertensive rat aortic strips. Amer. J. Physiol.198, 1019 (1960).

    PubMed  Google Scholar 

  • Mislin, H., Zur Funktionsanalyse des Hilfsherzens (Vena portae) der weißen Maus (Mus musculus f. alba). Generalversamml. der Schweiz. Zoolog. Ges. Genf 1963, S. 317.

  • Mislin, H., Vergleichende angiologische Untersuchungen der intramuralen Erregungsleitung in aktiv-pulsierenden Blutgefäß-Präparaten. Verh. Dtsch. Zoolog. Ges. Heidelberg 1967, S. 105.

  • Mislin, H., Der Einfluß der Atemgase auf die Tätigkeit der isolierten, autorhythmischen Vena portae der weißen Maus (Mus musculus f. alba). Rev. Suisse Zool.75, (1968).

  • Pickford, M., Oxytocin. Eds.: R. Caldeyro-Barcia und H. Heller. S. 68 (Oxford 1961).

  • Rhodin, J. A. G., Fine structure of vascular walls in mammals. With special reference to smooth muscle components. Physiol. Rev.42, Suppl. 5, 48 (1962).

    PubMed  Google Scholar 

  • Rogers, L. A., R. A. Atkinson andJ. P. Long, Responses of isolated perfused arteries to catecholamines and nerve stimulation. Amer. J. Physiol.209, 376 (1965).

    PubMed  Google Scholar 

  • Rolshoven, E., Zur Problematik der Vena portae. Ann. Univ. Sarav. Med.6, 304 (1968).

    Google Scholar 

  • Schipp, R., Zur Feinstruktur der mesenterialen Lymphgefäße (Cavia porcellus). Z. Zellforschg.67, 799 (1965).

    Google Scholar 

  • Somlyo, A. P., R. L. Sandberg andA. V. Somlyo, Vascular smooth muscle contraction as a function of stimulus frequency. Dig. of the 6th Internat. Conference on Med. Electronics and Biological Engineering, 44 (1965).

  • Somlyo, A. V., C. Woo andA. P. Somlyo, Responses of nerve free vessels to vasoactive amines and polypeptides. Amer. J. Physiol.208, 748 (1965).

    PubMed  Google Scholar 

  • Somlyo, A. V., R. L. Sandberg andA. P. Somlyo, Pharmacologically heterogenous smooth muscle cell distribution in blood vessels. J. Pharmacol. exp. Ther.149, 106 (1965).

    PubMed  Google Scholar 

  • Somlyo, A. V. andA. P. Somlyo, Effect of angiotensin and beta-adrenergic stimulation on venous smooth muscle. Amer. Heart J.71, 568 (1966).

    PubMed  Google Scholar 

  • Sparks, H. V. jr andD. F. Bohr, Effect of stretch on passive tension and contractility of isolated vascular smooth muscle. Amer. J. Physiol.202, 835 (1962).

    PubMed  Google Scholar 

  • Speden, R. N., Effect of initial strip length on the noradrenaline-induced isometric contraction of arterial strips. J. Physiol.154, 15 (1960).

    Google Scholar 

  • Sutter, M. C., The pharmacology of isolated veins. Brit. J. Pharmacol.24, 742 (1965).

    PubMed  Google Scholar 

  • Texter, E. C., C. C. Chou, S. Merrill, H. C. Laureta andE. D. Frohlich, Direct effects of vasoactive agents on segmental resistance of the mesenteric and portal circulation. J. Lab. clin. Med.64, 624 (1964).

    PubMed  Google Scholar 

  • Uchida, E., D. F. Bohr andS. W. Hoobler, A method for studying isolated resistance vessels from rabbit mesentery and brain and their responses to drugs. Circulat. Res.21, 525 (1967).

    PubMed  Google Scholar 

  • Voth, D., Über das Verhalten von Adenosintriphosphatasen in verschiedenen Rattenhirnfraktionen unter besonderer Berücksichtigung des Einflusses mono- und bivalenter Kationen. Brain Research4, 60 (1967).

    PubMed  Google Scholar 

  • Voth, D., K. Jork undA. Schäfer, Über den ATP-induzierten Kontraktionseffekt von Mitochondrien und zwei Mikrosomenfraktionen aus Rattenhirn in vitro. Naunyn-Schmiedebergs Arch. Pharmakol. exp. Path.257, 346 (1967).

    Google Scholar 

  • Voth, D., K. Jork undK. Schürmann, Über Schwellungs- und Kontraktionsphänomene in vitro bei Mitochondrien und Mikrosomen aus Rattenhirn, In: G. Kienle (Ed.): Hydrodynamik, Elektrolyt- und Säure-Basen-Haushalt im Liquor und Nervensystem. S. 166 (Stuttgart 1967).

  • Voth, D. undA. Schäfer, Vergleichende photometrische und elektronenmikroskopische Untersuchungen an isolierten Rattenhirn-Mitochondrien und-Mikrosomen in vitro unter den Bedingungen der osmotischen Schwellung und ATP-induzierten Kontraktion. Brain Research10, 322 (1968).

    PubMed  Google Scholar 

  • Voth, D., A. Schäfer undK. Jork, Zur photometrischen Messung von Volumenänderungen isolierter Zellorganellen (Vergleichende elektronenmikroskopische und photometrische Untersuchungen an Hirnmitochondrien und-mikrosomen in vitro). Naunyn-Schmiedebergs Arch. Pharmakol. exp. Path.260, 215 (1968).

    Google Scholar 

  • Voth, D., R. Schipp andM. Agsten, Experimental investigations—in vitro—on the influence of various cations and drugs on the spontaneous activity of vascular smooth muscle. Naunyn-Schmiedebergs Arch. Pharmakol. exp. Path.264, 321 (1969).

    Google Scholar 

  • Waugh, W. H., Vascular smooth muscle contraction induced by epinephrine in chloride-deficient electrolyte media. Physiologist5, 228 (1962).

    Google Scholar 

  • Waugh, W. H., Role of calcium in contractile excitation of vascular smooth muscle by epinephrine and potassium. Circulat. Res.11, 927 (1962).

    PubMed  Google Scholar 

Download references

Author information

Author notes

  1. D. Voth

    Present address: Neurochirurgischen Klinik der Johannes Gutenberg-Universität Mainz, Langenbeckstraße 1, 65, Mainz

  2. R. Schipp

    Present address: Inst. f. zoolog. Physiol. der Universität Mainz, Saarstraße 21, 65, Mainz

Authors and Affiliations

  1. Neurochirurgischen Klinik der Johannes Gutenberg-Universität Mainz, Langenbeckstraße 1, 65, Mainz

    R. Schipp, M. Agsten, K. Schürmann, M. Kohlhardt & J. Dudek

Authors
  1. D. Voth
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Schipp
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Agsten
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. Schürmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Kohlhardt
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. Dudek
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Mit 16 Abbildungen in 27 Einzeldarstellungen

Rights and permissions

Reprints and permissions

About this article

Cite this article

Voth, D., Schipp, R., Agsten, M. et al. Untersuchungen über den Einfluß des Kationenmilieus und verschiedener Pharmaka auf die Kontraktilität und Autorhythmik eines spontan aktiven glatten Gefäßmuskels in vitro. Archiv für Kreislaufforschung 60, 364–387 (1969). https://doi.org/10.1007/BF02119712

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02119712

Search

Navigation