Mycopathologia et mycologia applicata

, Volume 12, Issue 1, pp 67–76 | Cite as

Experimental fungus granuloma as seen from comparative exanthematology

  • Kasuke Ito


Here is presented a case of the experimental production of fungus granuloma on the ears of rabbits due to a second dorsal inoculation with tr. mentagr., var. ast. This tuberculoid granuloma is preceded or accompanied by fungus phlebitis and occasionally associated with arteritis or perifolliculitis granulomatosa on the ears. These reactions (granuloma, phlebitis, arteritis and perifolliculitis) are regarded as almost certainly falling into a cathegory of trichophytid as demonstrated by histology, serology, trichophytin and blood-cultivation. Also, these reactions are comparable to the cases of human fungus “id” reactions and tuberculous reinfection lesions in man. Then, similar fungus granulomas were artificially produced on the ears and in both lungs etc. by disseminate reinfection with the tr. ast. via cardiac route in rabbits, which had immunized by a dorsal infection with the tr. Summed up, this work is concerned with experimental fungus granuloma as seen from comparative exanthematology of mycid with other “id”, tuberculid in particular. We consider the fungus allergic granulomatous reactions as partial manifestations of general immune reaction (including trichophytemia), regardless whether fungi in the lesions activate in loco or result from fungus foci via blood circulation. Also, emphasis is placed upon an evaluation of crude polysaccharide (from the tr. mechanically disintegrated) as antigen or trichophytin (used for serology or trichophytin reaction).


Immune Reaction Polysaccharide Blood Circulation Experimental Production Phlebitis 
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  1. Brocq-Rousseu, Urbain, A. &Barotte, J. 1927. Anticorps dans les teignes experimentales: Zbl. Haut- u. Geschlechtskr.21: 853.Google Scholar
  2. Brunsgaard, 1922. Über hämatogene Trichophytie: Arch. Dermat. & Syph.138: 381.Google Scholar
  3. Bukovsky', J. 1900. Ein Beitrag zur Kentnis der experimentellen und klinischen Eigenschaften des Achorion Schönlein: Arch. Dermat. & Syph.51: 365.Google Scholar
  4. Falchi, G. 1927. Trichophytid mit Kultur des Tr. plicatile in strömendem Blut: Derm. Z.18, 891.Google Scholar
  5. Fried, M. &Segal, B. 1928. Beiträge zur experimentellen, auf hämatogenem Wege hervorgerufenen Dermatomykose, mit Berücksichtigung der Zirkulationsdauer der Parasiten im Blutkreislauf: Derm. Wschr.87, 1426.Google Scholar
  6. Henrici, A. T. 1939. Experimental trichophytid in guinea pigs: Proc. Soc. exp. Biol. Med.41, 349.Google Scholar
  7. Jadassohn, W. 1927. Beitrag zur Genese der Allergie bei Impfmykosen: Arch. Dermat. & Syph. 153: 476.Google Scholar
  8. Jessner, M. 1921. Zur Pathogenese der Thrichophytide: Arch. Dermat. & Syph.136: 416.Google Scholar
  9. Kogoj, F. 1926. Experimentelle Beiträge zur Lehre von den Dermatomykosen mit besonderer Berücksichtigung der Lokalisations-bestimmung hämatogener Infektionen: Arch. Dermat. u. Syph.150: 333.Google Scholar
  10. Kogoj, F. 1928. Hämatogene Dermatomykosen: nach subkutaner und intramuskulärer Infektion: Arch. Dermat. u. Syph.154, 463.Google Scholar
  11. Saeves, I. 1916. Experimentelle Beiträge zu Dermatomykosen: Arch. Dermat. u. Syph.,121: 161.Google Scholar
  12. Smolka, 1928. Experimentelle Beiträge zur Frage der hämatogenen Dermatomykosen: Arch. Dermat. u. Syph.154, 519.Google Scholar
  13. Sulzberger, M. B. 1928. The Pathogenesis of Trichophytids: Arch. Dermat. a. Syph.,18, 891.Google Scholar

Copyright information

© Uitgeverij Dr. W. JUNK 1960

Authors and Affiliations

  • Kasuke Ito
    • 1
  1. 1.Department of DermatologyGifu Medical CollegeGifu-CityJapan

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