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Mycopathologia et mycologia applicata

, Volume 12, Issue 1, pp 67–76 | Cite as

Experimental fungus granuloma as seen from comparative exanthematology

  • Kasuke Ito
Article
  • 6 Downloads

Summary

Here is presented a case of the experimental production of fungus granuloma on the ears of rabbits due to a second dorsal inoculation with tr. mentagr., var. ast. This tuberculoid granuloma is preceded or accompanied by fungus phlebitis and occasionally associated with arteritis or perifolliculitis granulomatosa on the ears. These reactions (granuloma, phlebitis, arteritis and perifolliculitis) are regarded as almost certainly falling into a cathegory of trichophytid as demonstrated by histology, serology, trichophytin and blood-cultivation. Also, these reactions are comparable to the cases of human fungus “id” reactions and tuberculous reinfection lesions in man. Then, similar fungus granulomas were artificially produced on the ears and in both lungs etc. by disseminate reinfection with the tr. ast. via cardiac route in rabbits, which had immunized by a dorsal infection with the tr. Summed up, this work is concerned with experimental fungus granuloma as seen from comparative exanthematology of mycid with other “id”, tuberculid in particular. We consider the fungus allergic granulomatous reactions as partial manifestations of general immune reaction (including trichophytemia), regardless whether fungi in the lesions activate in loco or result from fungus foci via blood circulation. Also, emphasis is placed upon an evaluation of crude polysaccharide (from the tr. mechanically disintegrated) as antigen or trichophytin (used for serology or trichophytin reaction).

Keywords

Immune Reaction Polysaccharide Blood Circulation Experimental Production Phlebitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Uitgeverij Dr. W. JUNK 1960

Authors and Affiliations

  • Kasuke Ito
    • 1
  1. 1.Department of DermatologyGifu Medical CollegeGifu-CityJapan

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