Summary
Platelets of 235 blood donors were typed for FXIIIA polymorphism using agarose gel electrophoresis with subsequent immunofixation with anti-FXIIIA serum. The allele frequencies obtained (FXIIIA*1 = 0.7787, FXIIIA*2 = 0.2212) are in agreement with previously published data for Caucasoid populations. FXIIIA may be an additional valuable marker for paternity and linkage studies.
Zusammenfassung
Wir haben Thrombozytenkonserven von 109 und Thrombozyten-“pellets” aus Plasma von 126 Spendern aus dem Köln-Bonner Raum mit der Agarosegel-Elektrophorese mit nachfolgender Immunfixation auf den Faktor XIIIA-Polymorphismus untersucht. Die gefundenen Allelfrequenzen für FXIIIA*1 von 0.7787 und FXIIIA*2 von 0.2212 stehen in guter Übereinstimmung mit anderen, für die weiße Rasse erhobenen Frequenzen. Der FXIIIA-Polymorphismus kann ohne Bedenken in die Abstammungsbegutachtung einbezogen werden.
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Herrn Prof. Dr. O. Grüner zum 65. Geburtstag gewidmet.
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Rittner, C., Wolf, T. Zur Populationsgenetik des Gerinnungsfaktor XIII A Polymorphismus. Z Rechtsmed 91, 225–229 (1984). https://doi.org/10.1007/BF02116425
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DOI: https://doi.org/10.1007/BF02116425