Immunogenetics

, Volume 31, Issue 5–6, pp 386–388 | Cite as

TheHLA-DNA (DZA) gene is correctly expressed as a 1.1 kb mature mRNA transcript

  • John A. T. Young
  • John Trowsdale
Brief Communications

Keywords

mRNA Transcript Mature mRNA Mature mRNA Transcript 

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References

  1. Auffray, C., Lillie, J. W., Arnot, D., Grossberger, D., Kappes, D., and Strominger, J. L.: Isotypic and allotypic variation of human class II histocompatibility antigen α chains.Nature 308: 327–333, 1984PubMedGoogle Scholar
  2. Bodmer, J., Bodmer, W., Heyes, J., So, A., Tonks, S., Trowsdale, J., and Young, J.: Identification of HLA-DP polymorphism with DPα and DPβ probes and monoclonal antibodies: correlation with primed lymphocyte typing.Proc Natl Acad Sci USA 84:4596–4600, 1987PubMedGoogle Scholar
  3. Carra, G. and Accolla, R. S.: Structural analysis of human la antigens reveals the existence of a fourth molecular subset distinct from DP, DQ, and DR molecules.J Exp Med 165: 47–63, 1987PubMedGoogle Scholar
  4. Gubler, U. and Hoffmann, B. J.: A simple and very efficient method for generating cDNA libraries.Gene 25: 263–269, 1983PubMedGoogle Scholar
  5. Inoko, H., Ando, A., Kimura, M., and Tsuji, K.: Isolation and characterisation of the cDNA clone and genomic clones of a new HLA class II antigen heavy chain, DOα.J Immunol 135: 2156–2159, 1985PubMedGoogle Scholar
  6. Okada, K., Prentice, H. L., Boss, J. M., Levy, D. J., Kappes, D., Spies, T., Raghupathy, R., Mengler, R. A., Auffray, C., and Strominger, J. L.: Gene organisation of DC and DX sub-regions of the human major histocompatibility complex.Proc Natl Acad Sci USA 82: 3410–3414, 1985PubMedGoogle Scholar
  7. Sanger, F., Coulson, A. R., Barrell, B. G., Smith, A. J. H., and Roe, B. A.: Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing.J Mol Biol 143: 161–178, 1980PubMedGoogle Scholar
  8. Tonnelle, C., DeMars, R., and Long, E. O.: DOβ; a new β chain gene with a distinct regulation of expression.EMBO J 4: 2839–2847, 1985PubMedGoogle Scholar
  9. Trowsdale, J. and Kelly, A. P.: The human class II a chain gene DZα is distinct from genes in the DP, DQ and DR sub-regions.EMBO J 4: 2231–2237, 1985PubMedGoogle Scholar
  10. Trowsdale, J., Young, J. A. T., Kelly, A. P., Austin, P. J., Carson, S., Meunier, H., So, A., Ehrlich, H. A., Spielman, R. S., Bodmer, J., and Bodmer, W.: Structure, sequence and polymorphism in the HLA-D region.Immunol Rev 85: 135–173, 1985Google Scholar
  11. Trowsdale, J., Groves, V., and Arnason, A.: Limited MHC polymorphism in whales.Immunogeneties 29: 19–24, 1989Google Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • John A. T. Young
    • 1
  • John Trowsdale
    • 1
  1. 1.Human Immunogenetics LaboratoryImperial Cancer Research FundLondon WC2A 3PXUnited Kingdom

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