Skip to main content
Log in

Multicenter Spanish study of ciprofloxacin susceptibility in gram-negative bacteria

  • Notes
  • Published:
European Journal of Clinical Microbiology and Infectious Diseases Aims and scope Submit manuscript

Abstract

The susceptibility of 2,426 gram-negative bacteria obtained from 18 Spanish hospitals to ciprofloxacin was evaluated. Among different medical centers, susceptibility to ciprofloxacin ranged from 83 to 100 % forEnterobacteriaceae, from 35 to 100 % forPseudomonas aeruginosa, from 0 to 100 % forXanthomonas maltophilia, Acinetobacter spp. and other gram-negative non-fermenting bacilli, and from 33 to 100 % forCampylobacter spp. All clinical isolates ofHaemophilus influenzae, Moraxella catarrhalis andNeisseria gonorrhoeae were susceptible to ciprofloxacin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Wolfson JS, Hooper DC: Fluoroquinolone antimicrobial agents. Clinical Microbiology Reviews 1989, 2: 378–424.

    PubMed  Google Scholar 

  2. Satta G, Siddu D, Cornaglia G, Pruna M: Ciprofloxacin and resistance to antibiotics in gram-positive and gramnegative bacteria. Reviews of Infectious Diseases 1988, 10, Supplement 1: 65–66.

    Google Scholar 

  3. Chin NX, Clynes N, Neu HC: Resistance to ciprofloxacin appearing during therapy. American Journal of Medicine 1989, 87, Supplement 5A: 28–31.

    PubMed  Google Scholar 

  4. Wiedemann B, Zuhlsdorf MT: Brief report: resistance development to fluoroquinolones in Europe. American Journal of Medicine 1989, 87, Supplement 5A: 9–11.

    Google Scholar 

  5. Barry AL, Fuchs PC, Pfaller MA, Allen SD, Gerlach EH: Prevalence of fluoroquinolone-resistant bacterial isolates in four medical centers during the first quarter of 1990. European Journal of Clinical Microbiology & Infectious Diseases 1990, 9: 906–908.

    Google Scholar 

  6. Femandes FJ, Ackerman VP: In vitro studies of ciprofloxacin and survey of resistance patterns in current isolates. Diagnostic Microbiology and Infectious Disease 1990, 13: 79–90.

    PubMed  Google Scholar 

  7. López-Brea M, Alarcón T: Isolation of fluoroquinolone-resistantEscherichia coli andKlebsiella pneumoniae from an infected Hickman catheter. European Journal of Clinical Microbiology & Infectious Diseases 1990, 9: 345–347.

    Google Scholar 

  8. Kresken M, Jansen A, Wiedemann B: Prevalence of resistance of aerobic gram-negative bacilli to broad-spectrum antibacterial agents: results of a multicenter study. Journal of Antimicrobial Chemotherapy 1990, 25: 1022–1024.

    PubMed  Google Scholar 

  9. Chamberland S, Malouin F, Rabin HR, Schollaardt T, Parr TR, Bryan LE: Persistence ofPseudomonas aeruginosa during ciprofloxacin therapy of a cystic fibrosis patient: transient resistance to quinolones and protein F-deficiency. Journal of Antimicrobial Chemotherapy 1990, 25: 995–1010.

    PubMed  Google Scholar 

  10. Ball P: Emergent resistance to ciprofloxacin amongstPseudomonas aeruginosa andStaphylococcus aureus: clinical significance and therapeutic approaches. Journal of Antimicrobial Chemotherapy 1990, 26, Supplement F: 165–179.

    Google Scholar 

  11. Gootz TD, Martin BA: Characterization of high-level quinolone resistance inCampylobacter jejuni. Antimicrobial Agents and Chemotherapy 1991, 35: 840–845.

    PubMed  Google Scholar 

  12. Aguiar JM, Chacón J, Cantón R, Baquero F: The emergence of highly fluoroquinolone-resistantEscherichia coli in community-acquired urinary tract infections. Journal of Antimicrobial Chemotherapy 1992, 29: 349–350.

    PubMed  Google Scholar 

  13. National Committee for Clinical Laboratory Standards: Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A2. NCCLS, Villanova, PA, 1990.

    Google Scholar 

  14. García-Rodríguez JA, García Sánchez JE, García García MI, García Sánchez E, Muñoz Bellido JL: In vitro activities of new oral β-lactams and macrolides againstCampy-lobacter pylori. Antimicrobial Agents and Chemotherapy 1989, 33: 1650–1651.

    PubMed  Google Scholar 

  15. Wolfson JS, Hooper DC: Bacterial resistance to quinolones: mechanisms and clinical importance. Reviews of Infectious Diseases 1989, 11, Supplement 5: 960–968.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Consortia

Additional information

Spanish Study Group on Quinolone Resistance: J.A. García-Rodríguez, J.E. García-Sánchez, E. García-Sánchez, I. Trujillano, M.I. García García, M.J. Fresnadillo (Salamanca); F. Baquero, J. Martínez Beltrán, E. Bouza, M. Rodríguez, M. López Brea, J.J. Picazo, F. Soriano (Madrid); E. Perea (Sevilla); M. de la Rosa, G. Piédrola (Granada); F. Martín Luengo (Murcia); J. García de Lomas, M. Gobernado (Valencia); R. Martín, G. Prats (Barcelona); R. Gómez Lus, M.L. Aisa (Zaragoza); R. Cisterna (Vizcaya); C. García Riestra (Santiago de Compostela).

Rights and permissions

Reprints and permissions

About this article

Cite this article

García-Rodríguez, J.A., Fresnadillo, M.J., García García, M.I. et al. Multicenter Spanish study of ciprofloxacin susceptibility in gram-negative bacteria. Eur. J. Clin. Microbiol. Infect. Dis. 14, 456–459 (1995). https://doi.org/10.1007/BF02114906

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02114906

Keywords

Navigation