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Extra-intestinal infections with multiply drug-resistantSalmonella typhimurium in hospitalized patients in jordan

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Abstract

During the 12-year period from 1978 to 1989,Salmonella typhimurium was the most frequently isolated serotype (592/1,500; 39.5 %) among all clinicalSalmonella isolates at Jordan University Hospital. Extra-intestinal infections due toSalmonella typhimurium accounted for 68 (11.5 %) isolates. A high percentage ofSalmonella typhimurium strains (52–90 %) were resistant to commonly used drugs in Jordan. Most of the antibiotic-resistant strains ofSalmonella typhimurium (10/12) examined which were from extra-intestinal sources contained a large plasmid (55 MDa) in addition to two to four small plasmids. These strains were also able to transfer most or part of their drug resistance in vitro. It is concluded that the invasive potential ofSalmonella typhimurium isolates is probably associated with the presence of a large virulence plasmid and multiple antibiotic resistance.

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  1. Department of Pathology — Microbiology, Faculty of Medicine, Jordan University, 11942, Amman, Jordan

    A. A. Shehabi

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  1. A. A. Shehabi
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Shehabi, A.A. Extra-intestinal infections with multiply drug-resistantSalmonella typhimurium in hospitalized patients in jordan. Eur. J. Clin. Microbiol. Infect. Dis. 14, 448–451 (1995). https://doi.org/10.1007/BF02114903

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