Abstract
The capsular types and the MICs of penicillin G and other antimicrobial agents were determined for 89 isolates ofStreptococcus pneumoniae. MICs of penicillin G ranged from 0.015 to 2 mg/l, with 29 % and 48 % of the isolates exhibiting intermediate resistance and complete resistance, respectively. All isolates were susceptible to teicoplanin and vancomycin, but 81 % and 43 % of the penicillin G-resistant strains were intermediately resistant to cefotaxime and imipenem, respectively. Strains belonged to 16 different capsular types: 73 % belonged to types 19F and 23F, and 97 % of strains belonging to these two types exhibited either intermediate or complete resistance to penicillin G.
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References
Watson DA, Musher DM, Jacobson JW, Verhoef J: A brief history of the pneumococcus in biomedical research: a panoply of scientific discovery. Clinical Infectious Diseases 1993, 17: 913–924.
Klugman KP: Pneumococcal resistance to antibiotics. Clinical Microbiology Reviews 1990, 3: 171–196.
National Committee for Clinical Laboratory Standards: Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. NCCLS, Villanova, PA, 1993.
Jorgensen JH, Swenson JM, Tenover FC, Ferraro MJ, Hindler JA, Murray PR: Development of interpretive criteria and quality control limits for broth microdilution and disk diffusion antimicrobial susceptibility testing ofStreptococcus pneumoniae. Journal of Clinical Microbiology 1994, 32: 2448–2459.
Otin CL, Morros TJ, Sala IS: Antibiotic susceptibility ofStreptococcus pneumoniae from pediatric patients. Journal of Antimicrobial Chemotherapy 1988, 22: 659–665.
Linares J, Pallarés R, Alonso T, Perez JL, Ayats J, Gudiol F, Viladrich PF, Martin R: Trends in antimicrobial resistance of clinical isolates ofStreptococcus pneumoniae in Bellvitge Hospital, Barcelona, Spain (1979–1990). Clinical Infectious Diseases 1992, 15: 99–105.
Gray MB, Dillon HC Jr: Clinical and epidemiologic studies of pneumococcal infection in children. Pediatric Infectious Diseases 1986, 5: 201–207.
Haglund LA, Istre GR, Pickett DA, Welch DF, Fine DP, the Pneumococcus Study Group: Invasive pneumococcal disease in central Oklahoma: emergence of high-level penicillin resistance and multiple antibiotic resistance. Journal of Infectious Diseases 1993, 168: 1532–1540.
Soares S, Kristinsson KG, Musser JM, Tomasz A: Evidence for the introduction of a multiresistant clone of serotype 6BStreptococcus pneumoniae from Spain to Iceland in the late 1980s. Journal of Infectious Diseases 1993, 168: 158–163.
Munoz R, Coffey TJ, Daniels M, Dowson CG, Laible G, Sasal J, Hakenbeck R, Jacobs M, Musser JM, Spratt BG, Tomasz A: Intercontinental spread of a multiresistant clone of serotype 23FStreptococcus pneumoniae. Journal of Infectious Diseases 1991, 164: 302–306.
Goldstein FW, Geslin P, Acar JF, the French Study Group: Comparative activity of teicoplanin and vancomycin against 400 penicillin susceptible and resistantStreptococcus pneumoniae. European Journal of Clinical Microbiology & Infectious Diseases 1994, 13: 33–34.
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Chong, Y., Lee, K., Kwon, O.H. et al. Capsular types and antimicrobial resistance ofStreptococcus pneumoniae isolated in Korea. Eur. J. Clin. Microbiol. Infect. Dis. 14, 528–531 (1995). https://doi.org/10.1007/BF02113433
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DOI: https://doi.org/10.1007/BF02113433