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Brain damage in rats following pentylenetetrazole and high pressure oxygen

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  • Pharmacologica
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Résumé

La pentylénetétrazole (PTZ) et l'oxygène à haute pression (OHP) ont des propriétés en commun; tous deux causent des convulsions et du dommage aux poumons chez les rats. Elles diffèrent en ce que l'OHP — mais non pas la PTZ — produit au cerveau une paralysie spastique. On a trouvé que la PTZ, donnée avant et non pas après l'exposition des rats à l'OHP, réduit la paralysie du cerveau.

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Authors and Affiliations

  1. Dimbleby Research Laboratory, St. Thomas' Hospital, S.E.1, London, England

    H. A. S. van den Brenk & J. W. Harris

  2. Laboratory of Radiobiology, University of California Medical Center, 94122, San Francisco, California, USA

    H. A. S. van den Brenk & J. W. Harris

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  1. H. A. S. van den Brenk
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  2. J. W. Harris
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van den Brenk, H.A.S., Harris, J.W. Brain damage in rats following pentylenetetrazole and high pressure oxygen. Experientia 26, 1327–1328 (1970). https://doi.org/10.1007/BF02113009

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  • DOI: https://doi.org/10.1007/BF02113009

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