Skip to main content
Log in

Der Einfluß der Entbindungsart auf die retroplazentare und periphere Serumkonzentration von HPL und SP-1

  • Published:
Archives of gynecology Aims and scope Submit manuscript

Summary

The concentrations of HPL and SP-1 were measured in retroplacental and peripheral serum in patients who had an elective Caesarean section and in patients who had a spontaneous vaginal delivery. The peripheral concentration of HPL was significantly lower after vaginal delivery than after elective Caesarean sections (p < 0.001). The retroplacental concentration of serum-SP-1 after vaginal delivery was significantly higher than after elective Caesarean section (p < 0.001). After elective Caesarean section the retroplacental concentration of SP-1 was significantly lower than the peripheral concentration (p < 0.001), but after vaginal delivery the mean retroplacental and peripheral serum-SP-1 values were about equal.

Zusammenfassung

Die Konzentration von HPL und SP-1 im retroplazentaren und im peripheren mütterlichen Serum wurde bei Fällen nach vaginaler Entbindung sowie bei Fällen nach primärer Sectio caesarea geprüft. Die Konzentration von HPL im peripheren Serum war bei der vaginalen Entbindung signifikant niedriger als bei der primären Sectio (p < 0,001).

Die retroplazentare SP-1-Konzentration fand sich bei der vaginalen Entbindung signifikant höher als bei der primären Sectio (p < 0,001). Während bei der primären Sectio die SP-1-Konzentration retroplazentar signifikant niedriger lag als an der Peripherie (p < 0,001), lagen die Mittelwerte retroplazentar und peripher bei der vaginalen Entbindung annähernd auf gleicher Höhe.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  1. Bohn H (1971) Nachweis und Charakterisierung von Schwangerschaftsproteinen in der menschlichen Plazenta sowie ihre quantitative immunologische Bestimmung im Serum schwangerer Frauen. Arch Gynäkol 210:440

    Google Scholar 

  2. Bohn H (1972) Nachweis und Charakterisierung von löslichen Antigenen in der menschlichen Plazenta. Arch Gynäkol 212:165

    Google Scholar 

  3. Cramer DW, Beck P, Makowski EL (1971) Correlation of gestational age with maternal HCS and maternal and fetal GH plasma concentrations during labour. Am J Obstet Gynecol 109:649

    PubMed  Google Scholar 

  4. England P, Lorrimer D, Fergueson JC, Moffat AM, Kelly AM (1974) HPL: watchdog of fetal distress. Lancet I:5

    Google Scholar 

  5. Gillard M, Letchworth AT, Chard T (1973) HPL levels in relation to initiation and maintenance of labour. Obstet Gynecol 41:774

    PubMed  Google Scholar 

  6. Gusdon JP, Yen SSC (1967) In vitro biosynthesis of human placental lactogen (HPL) by human placental tissue. Obstet Gynecol 30:635

    PubMed  Google Scholar 

  7. Home CW, Towler CM, Pugh-Humphreys RP, Thomson HW, Bohn H (1976) Pregnancy specific β1-glycoprotein — a product of the syncytiotrophoblast. Experientia 32:1197

    PubMed  Google Scholar 

  8. Klopper A, Hughes G (1978) Placental secretion of oestrogens and protein hormones. Arch Gynäkol 225:171

    Google Scholar 

  9. Lin TM, Halbert S (1976) Placental localization of human pregnancy associated proteins. Science 193:1249

    PubMed  Google Scholar 

  10. Mancini G, Carbonara AO, Heremans JP (1965) Immunochemical quantitation of antigens by single radial immunodiffusion. Int J Immunochem 2:235

    Google Scholar 

  11. Pavlou C, Chard T, Letchworth AT (1972) Circulating levels of human chorionic somatomammotrophin in late pregnancy: disappearance from the circulation after delivery, variation during labour and circadian variation. J Obstet Gynaecol Br Commonw 79:629

    PubMed  Google Scholar 

  12. Saxena BN, Emerson KJ, Selenko W (1969) Serum placenta lactogen (HPL) levels as an index of placental function. N Engl J Med 281:225

    PubMed  Google Scholar 

  13. Sciarra JJ, Kaplan SL, Grumbach MM (1963) Localization of antihuman growth hormone serum within the human placenta: evidence for a human chorionic “growth hormone — prolactine”. Nature 199:1005

    PubMed  Google Scholar 

  14. Smith R, Klopper A, Hughes G, Wilson G (1979) The compartimental distribution of oestrogens and pregnancy specific β1-glycoprotein. Br J Obstet Gynaecol 86:119

    PubMed  Google Scholar 

  15. Suwa S, Friesen H (1969) Biosynthesis of human placental lactoproteins and human placental lactogen (HPL) in vitro. Endocrinology 85:1037

    PubMed  Google Scholar 

  16. Tatarinov YS, Falaleeva DM, Kalashnikov VV, Tolokov BO (1976) Immunofluorescent localization of human pregnancy specific β-globulin in the placenta and chorioepithelioma. Nature 260:263

    Google Scholar 

  17. Tatra G (1977) Das schwangerschaftsspezifische β1-Glykoprotein (SP-1) in der zweiten Hälfte der Schwangerschaft. In: Probleme der perinatalen Medizin 4. W. Maudrich, Wien München Bern

    Google Scholar 

  18. Ylikorkala O (1973) Maternal serum HPL levels in normal and complicated pregnancy as an index of placental function. Acta Obstet Gynecol Scand [Suppl] 26:26

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tatra, G., Placheta, P. Der Einfluß der Entbindungsart auf die retroplazentare und periphere Serumkonzentration von HPL und SP-1. Arch. Gynecol. 229, 253–258 (1980). https://doi.org/10.1007/BF02108318

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02108318

Key words

Schlüsselwörter

Navigation